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Merck

860645P

Avanti

C8 Ceramide (d17:1/8:0)

Avanti Research - A Croda Brand 860645P, powder

别名:

N-octanoyl-D-erythro-sphingosine (C17 base)

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About This Item

经验公式(希尔记法):
C25H49NO3
分子量:
411.66
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (860645P-10mg)

製造商/商標名

Avanti Research - A Croda Brand 860645P

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC

一般說明

C8-ceramide or N-octanoyl-D-erythro-sphingosine (C17 base) is a synthetic cell-permeable sphingolipid. It is a combination of C17 analog of sphingosine and octanoic acid. Ceramides are the major lipid component in the outermost layer of the skin, the stratum corneum. C8 Ceramide plays a vital role in inducing apoptotic cell death.

應用

C8 Ceramide (d17:1/8:0) has been used to induce myriocin-treated malignant melanoma cells to increase endogenous ceramide levels.

包裝

5 mL Amber Glass Screw Cap Vial (860645P-10mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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J P Witty et al.
Endocrinology, 137(12), 5269-5277 (1996-12-01)
Recent studies have demonstrated that ovarian follicle atresia occurs extensively before follicle selection into the avian preovulatory hierarchy, and that this process is mediated via granulosa cell apoptosis. Subsequent to follicle selection, granulosa cells are inherently resistant to apoptosis, and
Y-S Lee et al.
Cell proliferation, 44(4), 320-329 (2011-06-08)
Melanoma is the most aggressive form of skin cancer, and it resists chemotherapy. Candidate drugs for effective anti-cancer treatment have been sought from natural resources. Here, we have investigated anti-proliferative activity of myriocin, serine palmitoyltransferase inhibitor, in the de novo
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain

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