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Merck

860595P

Avanti

C17 Lactosyl(β) Ceramide (d18:1/17:0)

Avanti Research - A Croda Brand 860595P, powder

别名:

D-Lactosyl-β-1,1′-N-Heptadecanoyl-D-erythro-Sphingosine

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About This Item

经验公式(希尔记法):
C47H89NO13
分子量:
876.21
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25
价格与库存信息目前不能提供

形狀

powder

包裝

pkg of 1 × 5 mg (860595P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 860595P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI

1S/C47H89NO13/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-39(52)48-35(36(51)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)34-58-46-44(57)42(55)45(38(33-50)60-46)61-47-43(56)41(54)40(53)37(32-49)59-47/h28,30,35-38,40-47,49-51,53-57H,3-27,29,31-34H2,1-2H3,(H,48,

InChI 密鑰

RXEAEJDDQFAFLW-NMZPIEEZSA-N

一般說明

Lactosylceramide (LacCer) is a glycosphingolipid. It consists of a hydrophobic ceramide lipid and a hydrophilic sugar moiety.[1] LacCer is expressed abundantly in the nervous system and myelin sheath.[2]

生化/生理作用

Lactosylceramide (LacCer) is a structural and signaling lipid.[2] It is implicated in signal transduction, cell adhesion and host-tissue pathogen interactions.[2][3] LacCer modulates cell proliferation and apoptosis. It is involved in regulating cellular stress response and microbial pathogenesis. LacCer regulates innate immune responses.[3] It helps in microbial attachment and also acts as an adhesion receptor for pathogens.[1]

包裝

5 mL Amber Glass Screw Cap Vial (860595P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharide, 191, 106-114 (2009)
Daniela Couto et al.
Chemistry and physics of lipids, 191, 106-114 (2015-09-01)
Galactosylceramide (GalCer) and lactosylceramide (LacCer) are structural and signaling lipids, playing important roles in signal transduction and cell adhesion. They are especially abundant in the nervous system and in important components of the myelin sheath. Although neurodegenerative disorders are associated
Jarod A Fincher et al.
Scientific reports, 9(1), 17508-17508 (2019-11-27)
Neutral lipids have been implicated in a host of potentially debilitating human diseases, such as heart disease, type-2 diabetes, and metabolic syndrome. Matrix-assisted laser desorption ionization (MALDI), the method-of-choice for mass spectrometry imaging (MSI), has led to remarkable success in

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