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Merck

857465W

Avanti

AEA-d4

C20:4 anandamide-d4, methanol solution

别名:

5Z,8Z,11Z,14Z-eicosatetraenoylethanolaminde-d4

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About This Item

经验公式(希尔记法):
C22H33 D4NO2
分子量:
351.56
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

methanol solution

包裝

pkg of 1 × 1 mL (857465W-1mg)

製造商/商標名

Avanti Research - A Croda Brand 857465W

濃度

1 mg/mL (857465W-1mg)

脂質類型

bioactive lipids
deuterated lipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NC([2H])([2H])C([2H])([2H])O

一般說明

Anandamide (N-arachidonoyl ethanolamine, NArE, AEA) belongs to a large family of amidated signaling lipids, the N-acyl ethanolamines (NAEs). C20:4 AEA is a 20 carbon length side chain with four double bonds, i.e. the arachidonoyl group in AEA.

生化/生理作用

Anandamide (N-arachidonoyl ethanolamine, NArE, AEA) is a receptor for cannabinoid receptor. AEA functions as a mediator for many physiological processes including inflammation, pain, and appetite. C20:4 AEA is capable of activating vanilloid receptor (VR).

包裝

2 mL Amber Glass Sealed Ampule (857465W-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

儲存類別代碼

3 - Flammable liquids

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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`Entourage?effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism
Smart D, et al.
British Journal of Pharmacology, 136(3), 452-458 (2002)
Gabriel M Simon et al.
The Journal of biological chemistry, 281(36), 26465-26472 (2006-07-05)
N-Acyl ethanolamines (NAEs) are a large class of signaling lipids implicated in diverse physiological processes, including nociception, cognition, anxiety, appetite, and inflammation. It has been proposed that NAEs are biosynthesized from their corresponding N-acyl phosphatidylethanolamines (NAPEs) in a single enzymatic
Gabriel M Simon et al.
The Journal of biological chemistry, 283(14), 9341-9349 (2008-01-30)
Anandamide (AEA) is an endogenous ligand of cannabinoid receptors and a well characterized mediator of many physiological processes including inflammation, pain, and appetite. The biosynthetic pathway(s) for anandamide and its N-acyl ethanolamine (NAE) congeners remain enigmatic. Previously, we proposed an

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