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化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (790427C-10mg)
製造商／商標名
Avanti Research™ - A Croda Brand 790427C
濃度
10 mg/mL (790427C-10mg)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Phosphatidylcholine is a zwitterionic glycerophospholipid, containing choline. It consists of a head and two tails. Head group contains choline and phosphate. Head is polar and water soluble. The tail group contains two fatty acyl chains esterified with glycerol. Tail group is non-polar and water-insoluble. Phosphatidylcholine is synthesized in the liver by phosphatidylethanolamine methyltransferase (PEMT) pathway. It is also synthesized by the Kennedy pathway and the Lands cycle.
應用
06:0 PC-d22 (1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine) has been used:
- as bicelles for lipid in HN-HN nuclear overhauser enhancement (NOE) detection
- as an internal standard in residual algal suspension for liquid chromatography-mass spectrometry analysis (LC-MS/MS)
- to produce bicelles to investigate C-peptide and membrane interaction by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY)
生化／生理作用
Phosphatidylcholine (PC) is a major component of the membrane bilayer. It is involved in the synthesis of signaling molecules. PC is the precursor for the synthesis of sphingomyelin and phosphatidylserine.
包裝
5 mL Clear Glass Sealed Ampule (790427C-10mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system
水污染物質分類（WGK）
WGK 3
Biochemistry of Lipids, Lipoproteins and Membranes (2015)
pH-dependent interaction between C-peptide and phospholipid bicelles
Unnerstaale S and Maler L
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012(1), 43-43 (2012)
Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
Moessinger C, et al.
BMC Cell Biology, 15(1), 43-43 (2014)
Metabolic and morphological changes of an oil accumulating trebouxiophycean alga in nitrogen-deficient conditions
Ito T, et al.
Metabolomics, 9(1), 178-187 (2013)
The unusual transmembrane partition of the hexameric channel of the hepatitis C virus
Chen W, et al.
Structure, 26(4), 627-634 (2018)
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