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Merck

T16403

Sigma-Aldrich

2,2′,4,4′-四羟基二苯甲酮

97%

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About This Item

线性分子式:
[(HO)2C6H3]2CO
CAS号:
分子量:
246.22
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

mp

198-200 °C (lit.)

SMILES 字串

Oc1ccc(c(O)c1)C(=O)c2ccc(O)cc2O

InChI

1S/C13H10O5/c14-7-1-3-9(11(16)5-7)13(18)10-4-2-8(15)6-12(10)17/h1-6,14-17H

InChI 密鑰

WXNRYSGJLQFHBR-UHFFFAOYSA-N

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應用


  • Urinary concentrations of bisphenol A, parabens and benzophenone-type ultra violet light filters in relation to sperm DNA fragmentation in young men: A chemical mixtures approach.: This study investigates the relationship between urinary concentrations of various chemicals, including benzophenone-type UV filters like 2,2′,4,4′-Tetrahydroxybenzophenone, and sperm DNA fragmentation. The findings highlight potential reproductive toxicity risks associated with exposure to these compounds (Kiwitt-Cárdenas et al., 2024).

  • Salting-out assisted liquid-liquid extraction combined with LC-MS/MS for the simultaneous determination of seven organic UV filters in environmental water samples: method development and application.: This paper discusses the development of a method for detecting organic UV filters, including 2,2′,4,4′-Tetrahydroxybenzophenone, in environmental water samples. The method offers a reliable way to monitor the presence of these compounds in the environment (Carve et al., 2023).

  • Novel visible-light-active P-g-CN-based α-Bi(2)O(3)/WO(3) ternary photocatalysts with a dual Z-scheme heterostructure for the efficient decomposition of refractory ultraviolet filters and environmental hormones: Benzophenones.: The study presents a new photocatalyst capable of degrading benzophenone-type UV filters, including 2,2′,4,4′-Tetrahydroxybenzophenone, under visible light. This development has significant implications for environmental cleanup technologies (Berekute et al., 2023).

  • Boosting elimination of sunscreen, Tetrahydroxybenzophenone (BP-2), from water using monopersulfate activated by thorny NanoBox of Co@C prepared via the engineered etching strategy: A comparative and mechanistic investigation.: This research explores a novel method for removing 2,2′,4,4′-Tetrahydroxybenzophenone from water using advanced nanotechnology, highlighting its effectiveness and potential for environmental applications (Khiem et al., 2023).

  • The binding mechanism of benzophenone-type UV filters and human serum albumin: The role of site, number, and type of functional group substitutions.: The study examines how benzophenone-type UV filters, including 2,2′,4,4′-Tetrahydroxybenzophenone, interact with human serum albumin, providing insights into their behavior in biological systems and potential health implications (Ma et al., 2023).

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1A

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Yeawon Kim et al.
Toxicology, 288(1-3), 18-26 (2011-07-06)
Endocrine disruptors (EDs) affect the function of animal reproductive systems. Recently, 2,2',4,4'-tetrahydroxybenzophenone (BP2), which is a component of UV protection products, was found to be an ED that interferes with the thyroid hormone (TH) axis. However, BP2 activity in the
Christiane Schlecht et al.
Toxicology, 205(1-2), 123-130 (2004-10-02)
The estrogen receptors (ERs) are members of a super family of ligand-activated transcription factors mediating estrogenic responses. A close functional kinship was found for the structurally related estrogen receptor-related receptor1 (ERR1), a constitutively active transcription factor. The aryl hydrocarbon receptor
Hubertus Jarry et al.
Toxicology, 205(1-2), 87-93 (2004-10-02)
The chemical industry has developed sun protection factor products, which contain a variety of so-called "UV screens", among others, benzophenones (BP). Based on the structure it can be assumed, that the variant BP2 may be a potent estrogenic endocrine disrupter
Michael H Hsieh et al.
The Journal of urology, 178(4 Pt 2), 1637-1642 (2007-08-21)
Additives such as benzophenone-2 are commonly used in cosmetic products and food container plastics to filter out ultraviolet light. In pregnant women exposure may result in transplacental transfer of benzophenone-2 to fetuses. Benzophenone-2 is estrogenic in vitro and in the
Christin J Weisbrod et al.
Toxicology and applied pharmacology, 225(3), 255-266 (2007-09-25)
The UV filter benzophenone-2 (BP-2) is largely used in personal care products such as cosmetics and in numerous other materials for UV protection. Like other UV filters, BP-2 has been found to be estrogenic in vitro and in vivo, but

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