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Merck
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文件

ALD00550

Sigma-Aldrich

丝氨酸水解酶抑制剂17

别名:

tert-Butyl 4-(1H-pyrazole-1-carbonyl)-1,4-diazepane-1-carboxylate, SHI-17

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About This Item

经验公式（希尔记法）:
C14H22N4O3
CAS号:
1622426-20-3
分子量:
294.35
分類程式碼代碼:
12352200
PubChem物質ID:
329772714
NACRES:
NA.22

形狀

solid

品質等級

100

SMILES 字串

O=C(N1CCCN(C(OC(C)(C)C)=O)CC1)N2N=CC=C2

InChI

1S/C14H22N4O3/c1-14(2,3)21-13(20)17-8-5-7-16(10-11-17)12(19)18-9-4-6-15-18/h4,6,9H,5,7-8,10-11H2,1-3H3

InChI 密鑰

SREDUUSCWDQNQK-UHFFFAOYSA-N

應用

Serine hydrolase inhibitors are small molecule fragments that react in vitro with the serine hydrolase class of proteins. They are amenable to further modification to create novel inhibitors of this class of protein.

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Katerina Otrubova et al.
Bioorganic & medicinal chemistry letters, 24(16), 3807-3813 (2014-07-20)
Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subset of compounds that serve

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