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Merck

74104

Sigma-Aldrich

4-(4,6-二甲氧基三嗪-2-基)-4-甲基吗啉盐酸盐

≥97.0% (calc. on dry substance, AT), for peptide synthesis

别名:

DMTMM, MMTM

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About This Item

经验公式(希尔记法):
C10H17ClN4O3
CAS号:
分子量:
276.72
Beilstein:
8026872
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22

product name

4-(4,6-二甲氧基三嗪-2-基)-4-甲基吗啉盐酸盐, 95% (HPLC)

品質等級

化驗

95% (HPLC)

形狀

powder

反應適用性

reaction type: Coupling Reactions

雜質

≤17 wt. % water

應用

peptide synthesis

儲存溫度

−20°C

SMILES 字串

[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

InChI

1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1

InChI 密鑰

BMTZEAOGFDXDAD-UHFFFAOYSA-M

應用

4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉盐酸盐可用作以下转化反应的缩合剂:
  • 羧酸和胺在四氢呋喃中发生缩合反应,产生相应的酰胺。
  • 羧酸与醇的酯化反应,产生相应的酯。
  • 在质子溶剂中,将羧酸转化为相应的Weinreb酰胺。

用作溶液和固相肽合成中的羧酸的活化剂;性能优于或相当于最畅销的偶联剂

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

198.5 °F - closed cup

閃點(°C)

92.5 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Esterification of carboxylic acids with alcohols by 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM).
Kunishima M
Synlett, 1999(08), 1255-1256 (1999)
Chameen Samarawickrama et al.
Cornea, 37(5), 609-616 (2017-11-28)
To describe the use of collagen-based alternatives to cyanoacrylate glue for the sealing of acute corneal perforations. A collagen analog comprising a collagen-like peptide conjugated to polyethylene glycol (CLP-PEG) and its chemical crosslinker were tested for biocompatibility. These CLP-PEG hydrogels
Tetrahedron, 55, 13159-13159 (1999)
Synthesis and characterization of 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methylmorpholinium chloride.
Kunishima M
Tetrahedron Letters, 40(29), 5327-5330 (1999)
Vianney Delplace et al.
Biomacromolecules, 21(6), 2421-2431 (2020-04-11)
A hydrogel that can deliver both proteins and cells enables the local microenvironment of transplanted cells to be manipulated with a single injection. Toward this goal, we designed a hydrogel suitable for the co-delivery of neural stem cells and chondroitinase

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