化驗
97%
mp
153-157 °C (lit.)
SMILES 字串
Cc1cc2cc(N)ccc2[nH]1
InChI
1S/C9H10N2/c1-6-4-7-5-8(10)2-3-9(7)11-6/h2-5,11H,10H2,1H3
InChI 密鑰
JQULCCZIXYRBSE-UHFFFAOYSA-N
應用
Reactant for preparation of:
- Cytotoxic and antimitotic agents
- Potential antimicrobial aminoketones
- Inhibitors of monoamine oxidase (MAO)
- Protein kinase c theta (PKCθ) inhibitors
- Factor Xa inhibitors
- Inhibitors of vascular endothelial growth factor type 2 (VEGFR-2)
- Demethylasterriquinone B1receptor ligands
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Bioorganic & medicinal chemistry, 22(23), 6655-6664 (2014-12-03)
Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by evaluating CYP2A6 inhibitory effect of novel formyl, alkyl amine or carbonitrile
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