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品質等級
化驗
97%
mp
320-322 °C (lit.)
SMILES 字串
CC1COc2c(F)c(F)cc3C(=O)C(=CN1c23)C(O)=O
InChI
1S/C13H9F2NO4/c1-5-4-20-12-9(15)8(14)2-6-10(12)16(5)3-7(11(6)17)13(18)19/h2-3,5H,4H2,1H3,(H,18,19)
InChI 密鑰
NVKWWNNJFKZNJO-UHFFFAOYSA-N
基因資訊
human ... CSNK2A1(1457)
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一般說明
(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid may be used in the preparation of the following:
- kynurenine aminotransferase II (KAT II) inhibitor, [(S)-(-)-9-(4-aminopiperazine-1-yl)-8-fluoro-3-methyl-6-oxo-2,3,5,6-tetrahydro-4H-1-oxa-3a-aza-phenalene-5-carboxylic acid]
- fused-ring derivatives
- N-desmethyllevofloxacin
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
7-Piperazinylquinolones with methylene-bridged nitrofuran scaffold as new antibacterial agents.
Medicinal Chemistry Research, 22(12), 5940-5947 (2013)
On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo.
Journal of Neurochemistry, 109(2), 316-325 (2009)
Antimicrobial agents and chemotherapy, 54(12), 5214-5221 (2010-09-22)
Quinolones rapidly kill bacteria by two mechanisms, one that requires protein synthesis and one that does not. The latter, which is measured as lethal action in the presence of the protein synthesis inhibitor chloramphenicol, is enhanced by N-1 cyclopropyl and
Journal of medicinal chemistry, 49(22), 6443-6450 (2006-10-27)
Due to the emerging role of protein kinase CK2 as a molecule that participates not only in the development of some cancers but also in viral infections and inflammatory failures, small organic inhibitors of CK2, besides application in scientific research
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