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Merck

421987

Sigma-Aldrich

双(六亚甲基)三胺

technical grade, 40%

别名:

6,6′-Iminodihexylamine, 双(6-氨基己基)胺

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About This Item

线性分子式:
NH2(CH2)6NH(CH2)6NH2
CAS号:
分子量:
215.38
Beilstein:
2323517
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

等級

technical grade

蒸汽壓力

<0.01 mmHg ( 25 °C)

濃度

40%

折射率

n20/D 1.49 (lit.)

bp

163-165 °C/4 mmHg (lit.)

mp

33-36 °C (lit.)

密度

0.85 g/mL at 20 °C (lit.)
0.931 g/mL at 25 °C

SMILES 字串

NCCCCCCNCCCCCCN

InChI

1S/C12H29N3/c13-9-5-1-3-7-11-15-12-8-4-2-6-10-14/h15H,1-14H2

InChI 密鑰

MRNZSTMRDWRNNR-UHFFFAOYSA-N

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一般說明

Bis(hexamethylene)triamine is an aliphatic polyamine. It is a spermidine analog and has been reported to lack the enhancing effect on mitochondrial Ca(2+) accumulation but shows inhibitory effect on the Ca(2+) and Pi-induced mitochondrial permeability transition.

應用

Bis(hexamethylene)triamine is the suitable reagent used in the synthesis of xylylated dimer of polyamine and as a solvent to coat amphiphilic polymer on CdSe/ZnS quantum dots (QDs) for enhanced water solubilization.
It may be used in the following studies:
  • Synthesis of bis(hexamethylene) triacetamide (BHTA) by acetylation.
  • As a precursors for the ZnO outgrowths on TiO2 nanofibers.
  • As organic bifunctional guest molecules for {W36} polyoxotungstate host compounds to form 1D chains of directly connected {W36} cluster units.

法律資訊

DuPont 产品

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

235.4 °F - closed cup

閃點(°C)

113 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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分析证书(COA)

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P A Marks et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(16), 6358-6362 (1989-08-01)
N,N'-Hexamethylenebisacetamide (HMBA) induces transformed cells to differentiate, accompanied by suppression of oncogenicity. Clinical trials have shown that HMBA can cause positive therapeutic responses in some cancer patients, but clinical efficacy may be limited, in part, by dose-related toxicity. Potential improvements
I Rustenbeck et al.
Biochemistry and molecular biology international, 38(5), 1003-1011 (1996-04-01)
The aliphatic polyamine bis(hexamethylene)triamine, a spermidine analogue, was found to lack the enhancing effect on mitochondrial Ca(2+) accumulation which is typical for the natural polyamines, spermidine and spermine. However, like spermine and spermidine, this compound had a significant inhibitory effect
Thomas McGlone et al.
Chemistry, an Asian journal, 4(10), 1612-1618 (2009-08-26)
The {W36} isopolyoxotungstate cluster provides a stable inorganic molecular platform for the binding of inorganic and organic guest molecules. This is achieved by a binding pocket formed by six terminal oxo ligands located in the central cavity of the all-inorganic
Titanium oxide nanofibers attached to zinc oxide nanobranches as a novel nano-structure for lithium ion batteries applications.
Kime HY.
Journal of Ceramic Processing Research, 11(4), 437-442 (2010)
Laurence Covassin et al.
Bioorganic & medicinal chemistry letters, 13(19), 3267-3271 (2003-09-03)
Dimeric norspermidine and spermidine derivatives are strong competitive inhibitors of polyamine transport. A xylyl tether was used for the dimerization of various triamines and spermine via a secondary amino group, and of putrescine via an ether or an amino group.

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