393711

2′,3′-二脱氧-3′-氟尿苷

95%

• 别名: 3′-氟-2′,3′-二脱氧尿苷
• 经验公式（希尔记法）: C₉H₁₁FN₂O₄
• CAS号: 41107-56-6
• 分子量: 230.19
• Beilstein: 6064366
• EC號碼: 415-360-8
• MDL號碼: MFCD00192015
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24864537
• NACRES: NA.22

属性

• 化驗: 95%
• 光學活性: [α]20/D +10.5°, c = 0.5 in 1 M NaOH
• mp: 184-188 °C (lit.)
• SMILES 字串: OC[C@H]1O[C@H](C[C@@H]1F)N2C=CC(=O)NC2=O
• InChI: 1S/C9H11FN2O4/c10-5-3-8(16-6(5)4-13)12-2-1-7(14)11-9(12)15/h1-2,5-6,8,13H,3-4H2,(H,11,14,15)/t5-,6+,8+/m0/s1
• InChI 密鑰: BKIUEHLYJFLWPK-SHYZEUOFSA-N

说明

一般說明

2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.

應用

2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:

• 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.
• 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H341
• 防範說明: P281
• 危險分類: Muta. 2
• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves