376868

2-(2-氨基苯基)吲哚

97%

• 经验公式（希尔记法）: C₁₄H₁₂N₂
• CAS号: 32566-01-1
• 分子量: 208.26
• MDL编号: MFCD00134432
• UNSPSC代码: 12352100
• PubChem化学物质编号: 24863471

属性

• 方案: 97%
• mp: 154-155 °C (lit.)
• SMILES字符串: Nc1ccccc1-c2cc3ccccc3[nH]2
• InChI: 1S/C14H12N2/c15-12-7-3-2-6-11(12)14-9-10-5-1-4-8-13(10)16-14/h1-9,16H,15H2
• InChI key: IAKRGXQCKYFJCB-UHFFFAOYSA-N

说明

一般描述

2-(2-Aminophenyl)indole is an indole derivative. It has been reported as an amination reagent. 2-(2-Aminophenyl)indole undergoes condensation with 4,5-dichloro-1,2,3-dithiazolium chloride (Appel salt) to afford new 6-cyanoindolo[3,2-c]quinoline derivatives, having pharmacological applications.

应用

2-(2-Aminophenyl)indole may be used in the preparation of novel indolo[1,2-c]quinazolines and benzimidazo[1,2-c]quinazolines. It may be used in the synthesis of mono and bis-indolo[1,2-c] quinazolines.

Reactant in:

• cascade reactions of benzopyranylidenemalonates with mono- and dinucleophiles

Reactant for preparation of:

• Mono-, bis-indolo[1,2-c]quinazolines as antimicrobial agents
• Isocryptolepine alkaloid with antimalarial activity
• Cyanoindolo[3,2-c]quinolines and benzimidazo[1,2-c]quinazolines as antitumor agents

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H315,H319,H335
• 预防措施声明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危险分类: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 靶器官: Respiratory system
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: dust mask type N95 (US), Eyeshields, Gloves