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Merck

373974

Sigma-Aldrich

聚(2-乙基-2-恶唑啉)

average Mw ~500,000, PDI 3‑4

别名:

PEOX, POx, PetOx, 聚 2-乙基恶唑啉, 聚乙氧基唑啉

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About This Item

线性分子式:
[-N(COC2H5)CH2CH2-]n
CAS号:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

形狀

solid

分子量

average Mw ~500,000

黏度

60-80 cSt, 10 % in H2O

密度

1.14 g/mL at 25 °C (lit.)

蛋白質二硫鍵異構酶

3‑4

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI 密鑰

NYEZZYQZRQDLEH-UHFFFAOYSA-N

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應用

这种聚(2-乙基-2-恶唑啉)聚合物是无定形和水溶性的,具有良好的温度稳定性。Jordan 及其同事证明了生物相容性,其在组织中无蓄积,并从血流中快速清除 。末端基团修饰的聚(2-乙基-2-恶唑啉)已与肽偶联 ,并被证明可以替代聚乙二醇 (PEG) 用于蛋白质和小分子药物的偶联 。

聚(乙烯醇)和聚(乙烯基吡咯烷酮)的潜在替代品。涂料中的粘合促进剂。热封和可再湿润的热熔胶

特點和優勢

非离子型水溶性热塑性塑料。具有比聚乙烯醇更优越的热稳定性。具有良好的熔体流动性、剪切稳定性和牛顿特性。水是室温 θ 溶剂。

外觀

N-丙酰基取代线性聚乙烯亚胺

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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J H Jeong et al.
Journal of controlled release : official journal of the Controlled Release Society, 73(2-3), 391-399 (2001-08-23)
A series of linear poly(ethylenimine) (L-PEI) containing varying amounts of cationic charge density in its backbone was produced by controlled hydrolysis of poly(2-ethyl-2-oxazoline) (PEtOz) for using as a nonviral DNA transfection agent. The effects of cationic charge density and molecular
Issa Katime et al.
Applied spectroscopy, 57(7), 829-834 (2003-12-09)
This paper reports an FT-IR study of blends of poly(mono-n-alkyl itaconates) with poly(N,N-dimethylacrylamide) (PDMA) and poly(ethyloxazoline) (PEOX). Strong hydrogen bonding has been found, and both polybases have shown similar acceptor strengths. Derivative techniques show asymmetric profiles for the free carbonyl
S R Winn et al.
Orthodontics & craniofacial research, 8(3), 183-190 (2005-07-19)
Bone repair strategies continue to be developed for alternatives to autografting, allogeneic implants of banked bone, and other bone substitutes. Efforts have included the delivery of potent growth and/or differentiation factors and the use of gene therapy. For bone regeneration
Sang Cheon Lee et al.
Journal of controlled release : official journal of the Controlled Release Society, 89(3), 437-446 (2003-05-10)
Polymeric micelles based on amphiphilic block copolymers of poly(2-ethyl-2-oxazoline) (PEtOz) and poly(epsilon -caprolactone) (PCL) were prepared in an aqueous phase. The loading of paclitaxel into PEtOz-PCL micelles was confirmed by 1H-NMR spectra. Paclitaxel was efficiently loaded into PEtOz-PCL micelles using
Chau-Hui Wang et al.
Biomacromolecules, 4(6), 1487-1490 (2003-11-11)
A new series of cationic, thermo-sensitive, and biodegradable poly(L-lactide)-poly(2-ethyl-2-oxazoline)-poly(L-lactide) (PLLA-PEOz-PLLA) triblock copolymers were synthesized by ring-opening polymerization. With increasing molecular weight and crystallinity of hydrophobic PLLA blocks, the critical micellization concentrations (CMC) occurred at lower concentration. The PLLA-PEOz-PLLA aqueous solution

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The introduction of polymers into the biomedical field has opened new avenues in tissue engineering, implant design, biosensing, and drug delivery.

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

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