372714

2,6-二甲氧基吡啶-3-羧酸

99%

• 别名: 2,6-二甲氧基烟酸
• 经验公式（希尔记法）: C₈H₉NO₄
• CAS号: 16727-43-8
• 分子量: 183.16
• MDL號碼: MFCD00075582
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24863158

属性

• 化驗: 99%
• mp: 140-144 °C (lit.)
• SMILES 字串: COc1ccc(C(O)=O)c(OC)n1
• InChI: 1S/C8H9NO4/c1-12-6-4-3-5(8(10)11)7(9-6)13-2/h3-4H,1-2H3,(H,10,11)
• InChI 密鑰: SDJQZCSCHUIITF-UHFFFAOYSA-N

说明

一般說明

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) is a piperidine derivative. It forms various organotin(IV) complexes and their antiproliferative action against pancreatic carcinoma (PANC-1), erythroleukemia (K562), and two glioblastoma multiform (U87 and LN-229) human cell lines has been evaluated.

應用

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) may be used in the preparation of the following organotin(IV) complexes (DMNIH=2,6-dimethoxynicotinic acid, BZDOH=1,4-benzodioxane-6-carboxylic acid, DMFUH=2,5-dimethyl-3-furoic acid and Cy=cyclohexyl):

• [SnCy₃-(DMNI)]
• [SnCy₃(BZDO)]
• [SnCy₃(DMFU)]
• [SnPh₂-(BZDO)₂]

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-dimethoxynicotinic acid, DMPH) may be used in the preparation of novel benzothiazolo naphthyridone carboxylic acid derivatives. It may be used in the preparation of following complexes, via reaction with different precursors [Ti(η⁵-C₅H₅)₂Cl₂], [Ti(η⁵-C₅H₄Me)₂Cl₂], [Ti(η⁵-C₅H₄SiMe₃)(η⁵-C₅H₅)Cl₂], [Ti(η⁵-C₅Me₅)Cl₃], SnMe₃Cl and GatBu₃:

• [Ti(η⁵-C₅H₅)₂(DMP-κO)₂]
• [Ti(η⁵-C₅H₄Me)₂(DMP-κO)₂]
• [Ti(η⁵-C₅H₄SiMe₃)(η⁵-C₅H₅)(DMP-κO)₂
• [Ti(η⁵-C₅Me₅)(DMP-κ²O,O′)₃]
• [SnMe₃(μ-DMP-κO:κO′)]_∞
• [GatBu₂(μ-DMP-κO:κO′)]₂

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves