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Merck

371858

Sigma-Aldrich

6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole hydrochloride

97%

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About This Item

经验公式(希尔记法):
C12H14N2O · HCl
CAS号:
分子量:
238.71
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:

化驗

97%

mp

288-290 °C (lit.)

SMILES 字串

Cl[H].COc1ccc2[nH]c3CNCCc3c2c1

InChI

1S/C12H14N2O.ClH/c1-15-8-2-3-11-10(6-8)9-4-5-13-7-12(9)14-11;/h2-3,6,13-14H,4-5,7H2,1H3;1H

InChI 密鑰

KRMJEIDSHZEQHJ-UHFFFAOYSA-N

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Benny B Tam et al.
Clinical & experimental optometry, 87(3), 171-174 (2004-06-10)
Pinoline is a pineal indoleamine naturally found in the retina. This study compared the effects of pinoline and vitamin E on the copper (I)-induced retinal lipid peroxidation (LPO). Porcine retinal homogenates were mixed with 120 micro M copper (I) solution.
W A Müller et al.
The International journal of developmental biology, 42(6), 825-828 (1998-09-04)
Support or inhibition of DAG-induced head formation: Hydra magnipapillata can be caused to form ectopic head structures by periodictreatmentwith PKC activators such as diacylglycerol (DAG). This ectopic head formation is supported by an extract from the ovine pineal gland that
Anne-Catherine Durand et al.
Journal of enzyme inhibition and medicinal chemistry, 22(5), 556-562 (2007-11-27)
In order to predict the antioxidant activity of 22 pinoline derivatives (1,2,3,4-tetrahydro-beta-carbolines), two dimensional quantitative-structure activity relationships (2D-QSAR) analysis of 19 hexahydropiridoindoles and 12 flavonoids was realized. Five statistically significant models were obtained from randomly constituted training sets (21 compounds)
R Pähkla et al.
Pharmacology & toxicology, 80(3), 122-126 (1997-03-01)
Pinoline (6-methoxy-1,2,3,4-tetrahydro-beta-carboline) is a naturally occurring compound in the mammalian body which inhibits 5-hydroxytryptamine (5-HT) uptake and exerts antidepressant-like behavioural effects in rats. The present study investigates the effects of pinoline on [3H]citalopram binding to the 5-HT transporter on rat
G Piñol-Ripoll et al.
Neuroscience letters, 405(1-2), 89-93 (2006-07-21)
Nitric oxide (NO) is a physiological neurotransmitter, a mediator of the excitatory neurotransmitter glutamate pathways that regulates several neuroendocrine functions, but excessive NO is toxic by itself and it interacts with superoxide radical (O(2)(-)) to form the peroxynitrite anion (ONOO(-)).

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