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Merck

300373

Sigma-Aldrich

2,3-二溴丙酰氯

97%

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About This Item

线性分子式:
BrCH2CHBrCOCl
CAS号:
分子量:
250.32
Beilstein:
1749801
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

化驗

97%

形狀

liquid

折射率

n20/D 1.542 (lit.)

bp

191-193 °C (lit.)

密度

2.181 g/mL at 25 °C (lit.)

SMILES 字串

ClC(=O)C(Br)CBr

InChI

1S/C3H3Br2ClO/c4-1-2(5)3(6)7/h2H,1H2

InChI 密鑰

HWKWYDXHMQQDQJ-UHFFFAOYSA-N

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應用

2,3-Dibromopropionyl chloride was used in synthesis of:
  • series of 2,3-diaminopropionanilides
  • enantiomers of 1,4-dideoxy-1,4-iminolyxitol and 1,4-dideoxy-1,4-iminoribitol
  • acromelic acid A

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

150.8 °F - closed cup

閃點(°C)

66 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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P A Tenthorey et al.
Journal of medicinal chemistry, 24(9), 1059-1063 (1981-09-01)
A series of 2,3-diaminopropionanilides was synthesized by acylation of mono- and disubstituted aniline derivatives with 2,3-dibromopropionyl chloride and subsequent amination with the appropriate secondary amines. The target compounds were evaluated in mice for antiarrhythmic efficacy against chloroform-induced tachycardia and for
Concise enantioselective synthesis of acromelic acid A.
Takano S, et al.
Journal of the American Chemical Society, 109(18), 5523-5524 (1987)
Chiral synthesis of both enantiomers of 1, 4-dideoxy-1, 4-immolyxitol and 1, 4-dideoxy-1, 4-iminoribitol.
Takano S, et al.
Tetrahedron Asymmetry, 3(6), 681-684 (1992)

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