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Merck

218448

Sigma-Aldrich

4-硝基喹啉 N -氧化物

98%

别名:

1-氧化-4-硝基喹啉, 4-NQO

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About This Item

经验公式(希尔记法):
C9H6N2O3
CAS号:
分子量:
190.16
Beilstein:
165756
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200

化驗

98%

mp

154-156 °C (lit.)

SMILES 字串

[O-][N+](=O)c1cc[n+]([O-])c2ccccc12

InChI

1S/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H

InChI 密鑰

YHQDZJICGQWFHK-UHFFFAOYSA-N

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说明
价格

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Carc. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges


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Kwame Osei-Sarfo et al.
Carcinogenesis, 34(11), 2673-2681 (2013-06-21)
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common type of cancer affecting humans worldwide. To determine the potential mechanisms by which chronic tobacco and alcohol abuse lead to HNSCC of the oral cavity, we have used
J Peter Svensson et al.
PloS one, 7(5), e37368-e37368 (2012-05-23)
Studies in Saccharomyces cerevisiae show that many proteins influence cellular survival upon exposure to DNA damaging agents. We hypothesized that human orthologs of these S. cerevisiae proteins would also be required for cellular survival after treatment with DNA damaging agents.
Jing Li et al.
Oral oncology, 49(4), 299-305 (2012-11-29)
Lymph node metastasis is one of the most important prognostic factors in oral squamous cell carcinoma. However, regional lymph node metastasis from oral cancer has barely been investigated in 4-nitroquinoline-1-oxide (4NQO) models. In this study, we developed a 4NQO-treated mouse
Leon F Stankowski et al.
Environmental and molecular mutagenesis, 52(9), 738-747 (2011-10-25)
As part of the Stage III Pig-a multilaboratory validation trial, we examined the induction of CD59-negative reticulocytes and total red blood cells (RET(CD59-) and RBC(CD59-) , respectively) in male Sprague Dawley(®) rats treated with 4-nitroquinoline-1-oxide (4NQO), for 28 consecutive days
Francesca Trotta et al.
International journal of food microbiology, 153(3), 275-280 (2011-12-20)
Yeasts isolated from Italian beverages and foods (wine and cheeses) were identified as Saccharomyces cerevisiae and Debaryomyces hansenii by sequencing the D1/D2 domain of the 26S rRNA gene and differentiated, at strain level, by microsatellite PCR fingerprinting and RAPD-PCR. All

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