方案
98%
mp
212 °C (dec.) (lit.)
SMILES字符串
Oc1ncccc1[N+]([O-])=O
InChI
1S/C5H4N2O3/c8-5-4(7(9)10)2-1-3-6-5/h1-3H,(H,6,8)
InChI key
BOAFCICMVMFLIT-UHFFFAOYSA-N
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一般描述
2-Hydroxy-3-nitropyridine reacts with phosphorus pentachloride and phosphoryl chloride to yield 2-chloro-3-nitropyridine.
应用
2-Hydroxy-3-nitropyridine was used in the synthesis of:
- 3-nitro-2-pyridyl β-D-galactoside
- 3-nitro-2-pyridyl N-acetyl-β-D-glucosaminide
- 5-amino-6-chloro-3-iodopyridine
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Nitropyridyl glycosides: new glycosyl donors for enzymatic transglycosylation.
Yasukochi T, et al.
Tetrahedron Letters, 40(36), 6585-6589 (1999)
Nanjing Zhang et al.
Bioorganic & medicinal chemistry letters, 13(3), 525-527 (2003-02-05)
Racemic 5-azidoepibatidine [(+/-)-1] was synthesized via 5-aminoepibatidine as a candidate photoaffinity ligand with exceptionally high affinity at the mammalian neuronal nicotinic receptors (K(i) values of 0.027 nM for alpha 4 beta 2 and 9.7 nM for alpha 7) and excellent
85. Nucleophilic displacement reactions in aromatic systems. Part I. Kinetics of the reactions of chloronitropyridines with aromatic amines and with pyridine.
Bishop RR, et al.
Journal of the Chemical Society, 437-446 (1952)
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