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Merck

190616

Sigma-Aldrich

2-羟基-3-硝基吡啶

98%

别名:

3-硝基-2-吡啶酮, 3-硝基-2-吡啶醇

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About This Item

经验公式(希尔记法):
C5H4N2O3
CAS号:
分子量:
140.10
Beilstein:
124474
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

98%

mp

212 °C (dec.) (lit.)

SMILES字符串

Oc1ncccc1[N+]([O-])=O

InChI

1S/C5H4N2O3/c8-5-4(7(9)10)2-1-3-6-5/h1-3H,(H,6,8)

InChI key

BOAFCICMVMFLIT-UHFFFAOYSA-N

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一般描述

2-Hydroxy-3-nitropyridine reacts with phosphorus pentachloride and phosphoryl chloride to yield 2-chloro-3-nitropyridine.

应用

2-Hydroxy-3-nitropyridine was used in the synthesis of:
  • 3-nitro-2-pyridyl β-D-galactoside
  • 3-nitro-2-pyridyl N-acetyl-β-D-glucosaminide
  • 5-amino-6-chloro-3-iodopyridine

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nitropyridyl glycosides: new glycosyl donors for enzymatic transglycosylation.
Yasukochi T, et al.
Tetrahedron Letters, 40(36), 6585-6589 (1999)
Nanjing Zhang et al.
Bioorganic & medicinal chemistry letters, 13(3), 525-527 (2003-02-05)
Racemic 5-azidoepibatidine [(+/-)-1] was synthesized via 5-aminoepibatidine as a candidate photoaffinity ligand with exceptionally high affinity at the mammalian neuronal nicotinic receptors (K(i) values of 0.027 nM for alpha 4 beta 2 and 9.7 nM for alpha 7) and excellent
85. Nucleophilic displacement reactions in aromatic systems. Part I. Kinetics of the reactions of chloronitropyridines with aromatic amines and with pyridine.
Bishop RR, et al.
Journal of the Chemical Society, 437-446 (1952)

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