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Merck

177148

Sigma-Aldrich

喹啉-3-羧酸

98%

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About This Item

经验公式(希尔记法):
C10H7NO2
CAS号:
分子量:
173.17
Beilstein:
126542
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

mp

277-280 °C (lit.)

SMILES 字串

OC(=O)c1cnc2ccccc2c1

InChI

1S/C10H7NO2/c12-10(13)8-5-7-3-1-2-4-9(7)11-6-8/h1-6H,(H,12,13)

InChI 密鑰

DJXNJVFEFSWHLY-UHFFFAOYSA-N

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一般說明

The antibacterial activity of 3-quinolinecarboxylic acid derivatives were evaluated.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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M P Wentland et al.
Journal of medicinal chemistry, 27(9), 1103-1108 (1984-09-01)
A series of novel 3-quinolinecarboxylic acid derivatives have been prepared and their antibacterial activity evaluated. These derivatives are characterized by fluorine attached to the 6-position and substituted amino groups appended to the 1- and 7-positions. Structure-activity relationship studies indicate that
Antonello Mai et al.
Journal of medicinal chemistry, 49(23), 6897-6907 (2006-12-13)
Starting from a yeast phenotypic screening performed on 21 compounds, we described the identification of two small molecules (9 and 18) able to significantly reduce the S. cerevisiae cell growth, thus miming the effect of GCN5 deletion mutant. Tested on
Ximei Liang et al.
Ecotoxicology (London, England), 24(7-8), 1566-1573 (2015-04-22)
The presence of antibiotics including norfloxacin in the aquatic environment may cause adverse effects in non-target organisms. But the toxic mechanisms of fluoroquinolone to fish species are still not completely elucidated. Thus, it is essential to investigate the response of

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