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化驗
98%
mp
120-122 °C (lit.)
SMILES 字串
OC(=O)c1ccoc1
InChI
1S/C5H4O3/c6-5(7)4-1-2-8-3-4/h1-3H,(H,6,7)
InChI 密鑰
IHCCAYCGZOLTEU-UHFFFAOYSA-N
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應用
3-糠酸可用作合成以下物质的反应物：
- 在无溶剂条件下通过歧化反应合成的呋喃-2,5-和呋喃-2,4-二羧酸。
- 与 2-甲基丁醛反应合成的(±)-Hyperolactone A。
- 人类疱疹病毒聚合酶的潜在非核苷抑制剂呋喃[2,3-b]吡啶-4-酮-5-羧酸酯衍生物。
生化／生理作用
3-糠酸在啮齿动物中具有降血脂活性。它能降低小鼠和大鼠的血清胆固醇和甘油三酸酯水平。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Concurrent formation of furan-2, 5-and furan-2, 4-dicarboxylic acid: unexpected aspects of the Henkel reaction.
Thiyagarajan S, et al.
Royal Society of Chemistry Advances, 3(36), 15678-15686 (2013)
I H Hall et al.
Pharmaceutical research, 2(5), 233-238 (1985-09-01)
2-Furoic acid, 3-furoic acid, 3,4-furan dicarboxylic acid and furyl-acrylic acid were evaluated for hypolipidemic activity in mice and rats. 2-Furoic acid was the most potent agent of the four tested, lowering serum cholesterol levels 41 % and serum triglyceride levels
Concurrent formation of furan-2, 5-and furan-2, 4-dicarboxylic acid: unexpected aspects of the Henkel reaction
Thiyagarajan S, et al.
Royal Society of Chemistry Advances, 3(36), 15678-15686 (2013)
Synthesis of 4-oxo-4, 7-dihydrofuro [2, 3-b] pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition
Schnute ME, et al.
Bioorganic & Medicinal Chemistry Letters, 18(14), 3856-3859 (2008)
First total synthesis of (?)-hyperolactone A
Ichinari D, et al.
Chemical Communications (Cambridge, England), (18), 1743-1744 (1997)
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