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Merck

158186

Sigma-Aldrich

乙二胺-N,N′-二乙酸

≥98%

别名:

EDDA, N,N′-乙烯二甘氨酸

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About This Item

线性分子式:
HOOCCH2NHCH2CH2NHCH2COOH
CAS号:
分子量:
176.17
Beilstein:
1778355
EC號碼:
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

化驗

≥98%

mp

224 °C (dec.) (lit.)

SMILES 字串

OC(=O)CNCCNCC(O)=O

InChI

1S/C6H12N2O4/c9-5(10)3-7-1-2-8-4-6(11)12/h7-8H,1-4H2,(H,9,10)(H,11,12)

InChI 密鑰

IFQUWYZCAGRUJN-UHFFFAOYSA-N

應用

乙二胺-N,N′-二乙酸(EDDA)是一种螯合剂,可用于合成:
  • 具有高蛋白酶体抑制性能的二元和三元铜(II)配合物。
  • 可以与氨基酸、肽或DNA单元络合的Pd(EDDA)配合物。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Jelena M Vujić et al.
European journal of medicinal chemistry, 45(9), 3601-3606 (2010-06-24)
Four novel bidentate N,N'-ligand precursors, including O,O'-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), L1 x 2 HCl-L4 x 2 HCl, of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid dihydrochloride [(S,S)-H(4)eddl]Cl(2) and the corresponding palladium(II) complexes 1-4, were prepared and characterized by IR, (1)H
Alma D Miranda-Olvera et al.
Bioconjugate chemistry, 18(5), 1560-1567 (2007-08-02)
Two synthetic procedures for HYNIC oxytocin labeling were developed: one based on an orthogonal protection approach and the other with prelabeled (Boc)HYNIC-(Fmoc) amino acids. Both procedures were compared and applied to the preparation of several HYNIC-oxytocin derivatives where ligand position
Hyun-Shik Chang et al.
Environmental science & technology, 40(16), 5089-5094 (2006-09-08)
Permanganate has been used for oxidation of nuclear wastes containing chelating agents such as ethylenediaminetetraacetic and nitrilotriacetic acids (EDTA and NTA) to improve separation of radionuclides and heavy metals from the wastes, butthe mechanisms of degradation of these and related
Clara L Santos-Cuevas et al.
Nuclear medicine communications, 29(8), 741-747 (2008-08-30)
The gastrin-releasing peptide receptor (GRP-R) is expressed in several normal human tissues and is overexpressed in various human tumors including breast, prostate, small-cell lung cancer and pancreatic cancer. Recently, 99mTc-EDDA/HYNIC-[Lys]-bombesin (99mTc-HYNIC-BN) was reported as a radiopharmaceutical with high stability in
Levente K Meszaros et al.
Dalton transactions (Cambridge, England : 2003), 40(23), 6260-6267 (2011-02-26)
6-Hydrazinonicotinic acid (HYNIC, 1) is a well-established bifunctional technetium-binding ligand often used to synthesise bioconjugates for radiolabelling with Tc-99m. It is capable of efficient capture of technetium at extremely low concentrations, but the structure of the labelled complexes is heterogeneous

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