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Merck

14501

Sigma-Aldrich

聚乙二醇双(胺)

Mw 2,000, carboxyl reactive, amine

别名:

O,O′-双(2-氨基乙基)聚乙二醇, 二氨基聚乙二醇, 聚乙二醇二胺, 聚氧乙烯二胺

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About This Item

线性分子式:
H2N(CH2CH2O)nCH2CH2NH2
CAS号:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

product name

聚乙二醇双(胺), Mw 2,000

形狀

powder

分子量

Mw 2,000

反應適用性

reagent type: cross-linking reagent
reactivity: carboxyl reactive

Ω-end

amine

α-end

amine

聚合物結構

shape: linear
functionality: homobifunctional

儲存溫度

−20°C

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

InChI 密鑰

IWBOPFCKHIJFMS-UHFFFAOYSA-N

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應用


  • Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo: Discusses the use of PEG-bis amine for creating polymeric nanocapsules aimed at enhancing targeted drug delivery (RI El-Gogary et al., 2014).

其他說明

制备可溶于有机溶剂的酶结合物的聚合物 ;前景良好的药物载体

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves


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L Kelemen et al.
Lab on a chip, 19(11), 1985-1990 (2019-05-03)
Whispering gallery mode (WGM) resonators are promising optical structures for microfluidic label-free biosensors mainly due to their high sensitivity, but from a practical point of view they present numerous constraints that make their use in real laboratory diagnosis application difficult.
K Kawasaki et al.
Chemical & pharmaceutical bulletin, 43(12), 2133-2138 (1995-12-01)
Hybrids of fibronectin-related peptides [Arg-Gly-Asp (RGD), Arg-Gly-Asp-Ser (RGDS)] and poly(ethylene glycol) (PEG) were prepared and their inhibitory effects on experimental metastasis in mice were examined. The inhibitory effect of RGD was markedly potentiated by hybrid formation with poly(ethylene glycol) #6000.
Urrotigoity, M. and Souppe, J.
Biocatalysis, 2, 145-145 (1989)
Alison G Patrick et al.
Macromolecular bioscience, 10(10), 1184-1193 (2010-07-02)
The design of hydrogels that simultaneously report protease activity and remove excess protease from solution is elucidated. The hydrogels, based on amino-PEGA, combine enzyme-specific peptides flanked with FRET complimented by charged amino acid residues that facilitate protease uptake via short
C S Lee et al.
Artificial organs, 21(9), 1002-1006 (1997-09-01)
Various modifications of alginate-poly-L-lysine microcapsules were made, such as the inclusion of polyethylenimine (PEI) or carboxyl methyl cellulose (CMC) in the core and the coating of bis(polyoxyethylene bis[amine]) (PEGA) onto the microcapsule membrane surface. A characterization of the modified microcapsules

商品

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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