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化驗
97%
形狀
solid
mp
195-200 °C (dec.) (lit.)
溶解度
95% ethanol: soluble 1g/150g at 20 °C
diethyl ether: soluble 1g/250g at 20 °C
chloroform: insoluble
water: slightly soluble
SMILES 字串
Nc1ncc(s1)[N+]([O-])=O
InChI
1S/C3H3N3O2S/c4-3-5-1-2(9-3)6(7)8/h1H,(H2,4,5)
InChI 密鑰
MIHADVKEHAFNPG-UHFFFAOYSA-N
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一般說明
2-氨基-5-硝基噻唑(ANT)是一种缺氧放射增敏药物 。ANT通过甲醇中的钯形成平面正方形络合物,即反式-[PdCl2(ANT)2]。
應用
2-氨基-5-硝基噻唑作为重氮组分用于合成单偶氮型分散染料 。在寡核苷酸和蛋白质的基质辅助激光解吸/电离飞行时间质谱研究中用作基质 。
訊號詞
Warning
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Radiation research, 112(2), 273-282 (1987-11-01)
Complexes of general formula [PtCl2(NH3)L] with one radiosensitizing ligand per platinum are compared with ligand L alone, complexes with two radiosensitizers per platinum [PtCl2L2], and their analogs with NH3 ligands, with respect to radiosensitizing properties and toxicity in CHO cells.
Bioorganic & medicinal chemistry letters, 20(12), 3537-3539 (2010-05-22)
Head group analogues of the antibacterial and antiparasitic drug nitazoxanide (NTZ) are presented. A library of 39 analogues was synthesized and assayed for their ability to suppress growth of Helicobacter pylori, Campylobacter jejuni, Clostridium difficile and inhibit NTZ target pyruvate:ferredoxin
2-amino-5-nitrothiazole.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 31, 71-77 (1983-07-01)
Synthesis and Spectral Properties of Hetaryl Monoazo dyes derived from 2-amino-5-nitrothiazole.
Orient. J. Chem., 27(4), 2011-2011 (1389)
Evaluation of 2-amino-5-nitrothiazole as a hypoxic cell radiosensitizer.
Radiation research, 90(3), 575-585 (1982-06-01)
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