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化驗
98%
形狀
solid
mp
146-149 °C (lit.)
SMILES 字串
COc1cc(OC)c2C=CC(=O)Oc2c1
InChI
1S/C11H10O4/c1-13-7-5-9(14-2)8-3-4-11(12)15-10(8)6-7/h3-6H,1-2H3
InChI 密鑰
NXJCRELRQHZBQA-UHFFFAOYSA-N
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一般說明
从茴香 H. Mann 的叶子和果实中分离和鉴定出 5,7-二甲氧基香豆素,该植物的果实用于构建莫霍克花环。它在细菌中诱导移码诱变。它还会在中国仓鼠细胞中引起致命的光敏化和姐妹染色单体交换的形成。
生化/生理作用
5,7-二甲氧基香豆素诱导小鼠(B16) 和人类(A375) 的分化和黑色素生成过程。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(17), 2200-2202 (2009-12-01)
To study the chemical constituents from Lobelia chinensis. The constituents were extracted with 95% EtOH, partitioned with different solvents, and isolated and purified by silica gel column chromatography and crystallization, their structures were elucidated by physico-chemical properties and spectroscopic data.
International journal of oncology, 32(2), 425-434 (2008-01-19)
In the present study we investigated the antiproliferative activity of 5,7-dimethoxycoumarin on the murine B16 and human A375 melanoma cell lines. The inhibitory concentration 50 (IC50) was estimated for each cell line by preliminary assay of tetrazolium salt reduction (MTT).
Earl Grey tea intoxication.
Lancet (London, England), 359(9316), 1484-1484 (2002-05-04)
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(1), 93-98 (2009-09-23)
Phototoxic and photo-genotoxic furocoumarins occur, e.g., in citrus species, parsnip, parsley, celery, and figs. They exhibit phototoxic and photo-genotoxic properties in combination with UV radiation, while less is known about the phototoxicity of the coumarin derivative limettin mainly found in
Chemical & pharmaceutical bulletin, 50(1), 118-120 (2002-02-05)
A new C-8 prenylated 5,7-dimethoxycoumarin named omphamurrayin was isolated from the leaves of Murraya paniculata var. omphalocarpa, and its structure was established as 5,7-dimethoxy-8-(1-oxo-2-senecioyl-3-methyl-3-butenyl)-2H-1-benzopyran-2-one on the basis of the spectroscopic evidence. The taxonomic status of M. paniculata var. omphalocarpa is
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