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F5135

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸

Name: N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸
Brand: SIGMA
Price: 248 SGD
Availability: InStock

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

1 of 1 reviewers received a sample product or took part in a promotion

collagenase substrate, chromogenic

别名:

FALGPA, N-[3-(2-呋喃基)丙烯酰基]-L-亮氨酸-甘氨酸-L-脯氨酸-L-丙氨酸

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5 MG

$248.00

25 MG

$959.00

100 MG

$2,830.00

$248.00

国内现货，预计发货时间2025年4月01日详情

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5 MG

$248.00

25 MG

$959.00

100 MG

$2,830.00

About This Item

经验公式（希尔记法）:

C₂₃H₃₂N₄O₇

CAS号:

78832-65-2

分子量:

476.52

MDL编号:

MFCD00133552

UNSPSC代码:

12352202

PubChem化学物质编号:

329799652

NACRES:

NA.32

$248.00

国内现货，预计发货时间2025年4月01日详情

新价格，新优惠！

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Slide 1 of 10

1 of 10

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C0130

胶原酶来源于溶组织梭菌

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C9891

胶原酶来源于溶组织梭菌

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C8051

胶原酶来源于溶组织梭菌

Sigma-Aldrich

C5138

胶原酶来源于溶组织梭菌

Sigma-Aldrich

S4760

N-琥珀酰-丙氨酸-丙氨酸-丙氨酸-p-硝基苯胺

Sigma-Aldrich

C7657

胶原酶来源于溶组织梭菌

Sigma-Aldrich

C9697

胶原酶来源于溶组织梭菌

Sigma-Aldrich

H3506

透明质酸酶来源于牛睾丸

Sigma-Aldrich

E1250

弹性蛋白酶来源于猪胰腺

Sigma-Aldrich

C6885

胶原酶来源于溶组织梭菌

产品名称

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸,

UniProt登记号

Q02111

储存温度

−20°C

SMILES字符串

CC(C)C[C@H](NC(=O)\C=C\c1ccco1)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(O)=O

InChI

1S/C23H32N4O7/c1-14(2)12-17(26-19(28)9-8-16-6-5-11-34-16)21(30)24-13-20(29)27-10-4-7-18(27)22(31)25-15(3)23(32)33/h5-6,8-9,11,14-15,17-18H,4,7,10,12-13H2,1-3H3,(H,24,30)(H,25,31)(H,26,28)(H,32,33)/b9-8+/t15-,17-,18-/m0/s1

InChI key

ZLFQNOJSYZSINX-PVJKAEHXSA-N

基因信息

mouse ... Prkcq(18761)

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Amino Acid Sequence

FA-Leu-Gly-Pro-Ala

一般描述

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸或FALGPA是一种类似于胶原蛋白一级结构的合成物质，可以被所有已知的胶原酶水解。[1]

应用

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸已用于采用GBS（B组链球菌）USF704进行的FALGPA检测。[2]

生化/生理作用

N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸或FALGPA可以被胶原酶水解，水解的最适pH为7.4。[1]

包装

无底玻璃瓶。内含物在插入的融合锥体内。

底物

胶原酶的底物。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Slide 1 of 5

1 of 5

Sigma-Aldrich

C8051

胶原酶来源于溶组织梭菌

Sigma-Aldrich

C9891

胶原酶来源于溶组织梭菌

Sigma-Aldrich

T3824

酪氨酸酶来源于蘑菇

Sigma-Aldrich

E7885

弹性蛋白酶来源于猪胰腺

Sigma-Aldrich

E1250

弹性蛋白酶来源于猪胰腺

Biochemical comparison of proteolytic enzymes present in rough- and smooth-surfaced capnocytophagas isolated from the subgingival plaque of periodontitis patients.

E Söderling et al.

Journal of periodontal research, 26(1), 17-23 (1991-01-01)

Four rough-surfaced (R) and three smooth-surfaced (S) clinical isolates of Capnocytophaga obtained from the subgingival plaque of periodontitis patients were studied for their peptidase and protease profiles. The results were compared with those obtained with C. gingivalis (which has a

The peptidolytic capacity of the spirochete system.

K K Mäkinen et al.

Medical microbiology and immunology, 185(1), 1-10 (1996-05-01)

Relatively scant chemical information has been available on the proteinases and peptidases of spirochetes in spite of the association of spirochetes with several serious infections known to plague humans and other animal species. This situation has partly resulted from difficulties

Inhibition of collagenase by Cr(III): its relevance to stabilization of collagen.

R Gayatri et al.

Biochimica et biophysica acta, 1524(2-3), 228-237 (2000-12-13)

Bacterial collagenase has now been reacted with a select series of Cr(III) complexes and modifications in the activity of chromium-modified collagenase has been deduced from the extent of hydrolysis of (2-furanacryloyl-L-leucyl-glycyl-L-prolyl-L-alanine), FALGPA. A homologous series of Cr(III) complexes with dimeric

Inhibitory role of silk cocoon extract against elastase, hyaluronidase and UV radiation-induced matrix metalloproteinase expression in human dermal fibroblasts and keratinocytes.

Jadi Praveen Kumar et al.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 18(5), 1259-1274 (2019-03-21)

Topical delivery of potent antioxidants maintain the redox balance of the skin, which leads to the downregulation of matrix metalloproteinase (MMP) expression and prevents UV radiation-induced photoaging. In this study, we aimed at investigating the inhibitory role of silk cocoon

Expression and characterization of the prtV gene encoding a collagenase from Vibrio parahaemolyticus in Escherichia coli.

M S Yu et al.

Microbiology (Reading, England), 145 ( Pt 1), 143-150 (1999-04-17)

The prtV gene, encoding a collagenase of Vibrio parahaemolyticus, was expressed in Escherichia coli and purified by affinity chromatography. The transformant E. coli BL21(DE3)(pPRT2) secreted the recombinant PrtV, and the highest enzyme activity was detected in the culture supernatant after

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实验方案

Enzymatic Assay of Collagenase (EC 3.4.24.3) using FALGPA (N-(3-[2-Furyl]acryloyl)-Leu-Gly-Pro-Ala)

To measure collagenase activity, N-(3-[2-Furyl]acryloyl)-Leu-Gly-Pro-Ala is used in a continuous spectrophotometric rate determination at 345 nm. Collagenase hydrolyzes collagen peptide bonds.

使用FALGPA（N-（3- [2-呋喃基]丙烯酰基）-Leu-Gly-Pro-Ala）进行的胶原酶酶法检测（EC 3.4.24.3）

在测定胶原酶活性时，使用N-（3-[2-呋喃基]丙烯酰基）-Leu-Gly-Pro-Ala在345nm处进行连续分光光度法测定。胶原酶水解胶原肽键。

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N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸

collagenase substrate, chromogenic

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About This Item

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产品名称

UniProt登记号

储存温度

SMILES字符串

InChI

InChI key

基因信息

说明

Amino Acid Sequence

一般描述

应用

生化/生理作用

包装

底物

安全信息

储存分类代码

WGK

闪点(°F)

闪点(°C)

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文件

分析证书(COA)

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