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B9385

Sigma-Aldrich

Boc-Val-Pro-Arg-7-酰胺基-4-甲基香豆素 盐酸盐

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About This Item

经验公式（希尔记法）:
C31H45N7O7
CAS号:
70375-24-5
分子量:
627.73
MDL號碼:
MFCD00058181
分類程式碼代碼:
12352204
PubChem物質ID:
24892134
NACRES:
NA.32

化驗

≥98% (TLC)

品質等級

200

形狀

powder

溶解度

water: 20 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

Cl.CC(C)C(NC(=O)OC(C)(C)C)C(=O)N1CCCC1C(=O)NC(CCCNC(N)=N)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C31H45N7O7.ClH/c1-17(2)25(37-30(43)45-31(4,5)6)28(42)38-14-8-10-22(38)27(41)36-21(9-7-13-34-29(32)33)26(40)35-19-11-12-20-18(3)15-24(39)44-23(20)16-19;/h11-12,15-17,21-22,25H,7-10,13-14H2,1-6H3,(H,35,40)(H,36,41)(H,37,43)(H4,32,33,34);1H

InChI 密鑰

ROQGJTZGLVLVIN-UHFFFAOYSA-N

一般說明

Boc-Val-Pro-Arg-AMC用作人类激肽释放素8的合成底物。

應用

Boc-Val-Pro-Arg-7-氨基-4-甲基香豆素盐酸盐已被用于
  • 在唾液蛋白cE5抑制试验中作为凝血酶的荧光底物
  • 作为凝血酶荧光底物的重组E. nipponicum丝氨酸蛋白酶抑制剂抑制试验
  • 作为血淋巴蛋白蛋白酶测定的底物

包裝

无底玻璃瓶。内含物装在锥底内插管中。

基底

一种用于凝血酶的荧光底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Sigma-Aldrich

T9326

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实验方案

Thrombin from Bovine Plasma

Thrombin is an endolytic serine protease that selectively cleaves the Arg–Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.

牛血浆凝血酶

凝血酶是一种内溶性丝氨酸蛋白酶，可选择性裂解纤维蛋白原的精氨酸-甘氨酸键，从而形成纤维蛋白并释放纤维蛋白肽A和B。

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