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Merck

TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

别名:
AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
物种:
UniProtKB ID:
基因ID:
  • Human(7048) Summary: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(21813) transforming growth factor, beta receptor II
  • Rat(81810) transforming growth factor, beta receptor II
  • Horse(100033860) transforming growth factor, beta receptor II (70/80kDa)
  • Zebrafish(30739) transforming growth factor, beta receptor II
  • chicken(396399) transforming growth factor, beta receptor II (70/80kDa)
  • domestic guinea pig(100718284) transforming growth factor, beta receptor II (70/80kDa)
  • dog(477039) transforming growth factor, beta receptor II (70/80kDa)
  • domestic cat(101091725) transforming growth factor, beta receptor II (70/80kDa)
  • cow(535376) transforming growth factor, beta receptor II (70/80kDa)
  • sheep(494191) transforming growth factor, beta receptor II (70/80kDa)
  • naked mole-rat(101704397) transforming growth factor, beta receptor II (70/80kDa)

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Antibodies

货号
说明
物种反应性
应用
Anti-TGFBR2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-TGF β Receptor II antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Anti-TGFBR2 Antibody, clone 1N11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-TGF β Receptor II (pSer225/250) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
Anti-TGFBR2 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human, rabbit
应用
western blot

Proteins

货号
说明
物种
TGFβR2 (190-端),活性,GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
Transforming Growth Factor-β2 human, TGF-β2, recombinant, expressed in NSO cells, powder, suitable for cell culture,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Tgfbr2,
物种
mouse