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Merck

SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

别名:
PAI, PAI-1, PAI1, PLANH1
物种:
UniProtKB ID:
基因ID:
  • Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
  • Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Custom & Knockdown Gene Products

ELISA

产品编号
说明
物种
人 PAI-1 ELISA 试剂盒, for serum, plasma, cell culture supernatant.,
物种
human
恒河猴PAI-1 ELISA试剂盒, for cell culture supernatants, plasma, and serum samples,
物种

Antibodies

产品编号
说明
物种反应性
应用
Anti-SERPINE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-SERPINE1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
Anti-PAI1/SERPINE1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-SerPINE1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, human, mouse, pig, rabbit, rat, sheep
应用
immunohistochemistry
western blot
Anti-PAI-1/Serpin E1 Antibody, clone 6L6Y7, Rabbit Monoclonal, ,
物种反应性
human
应用
western blot

Proteins

产品编号
说明
物种
血纤维蛋白溶酶原激活物抑制剂1(PAI-1) 人, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物种
human

esiRNA

产品编号
说明
物种
MISSION® esiRNA, targeting mouse Serpine1,
物种
mouse
MISSION® esiRNA, targeting human SERPINE1,
物种
human