PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
别名:
AGM7, GRB1, p85, p85-ALPHA
物种:
Human PIK3R1 (5295), Mouse Pik3r1 (18708), Rat Pik3r1 (25513), domestic guinea pig Pik3r1 (100730242), domestic cat PIK3R1 (100271864), cow PIK3R1 (282307), sheep PIK3R1 (101121455), chicken PIK3R1 (427171), Zebrafish pik3r1 (557176), dog PIK3R1 (487235)
UniProtKB ID:
基因ID:
- Human(5295) Summary: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
- Mouse(18708) phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
- Rat(25513) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
- domestic guinea pig(100730242) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
- domestic cat(100271864) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
- cow(282307) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
- sheep(101121455) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
- chicken(427171) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
- Zebrafish(557176) phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
- dog(487235) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
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Antibodies
货号
说明
物种反应性
应用
抗磷酸化PI3-激酶p85-α（pTyr607） 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-磷酸PI3激酶p85-α/γ (pTyr467/199) 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-PI3K P85 antibody, Rabbit monoclonal, clone SP62, recombinant, expressed in proprietary host, affinity isolated antibody,
物种反应性
bovine, frog, human, mouse, rat
应用
flow cytometry
immunohistochemistry
immunohistochemistry
Anti-PI3 Kinase Antibody, p85, from rabbit, purified by affinity chromatography,
物种反应性
bovine, human, mouse, rat, rhesus monkey
应用
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-PI3-kinase p85-α (pTyr607) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
western blot