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Merck

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

别名:
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
物种:
UniProtKB ID:
基因ID:
  • Human(5290) Summary: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008]
  • Mouse(18706) phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
  • Rat(170911) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • sheep(101110015) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • chicken(424971) phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • dog(488084) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • domestic guinea pig(100735084) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • naked mole-rat(101711934) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • domestic cat(101097413) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • cow(282306) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-PIK3CA antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
flow cytometry

immunofluorescence

western blot
Anti-PIK3CA antibody produced in rabbit, ,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-PIK3CA antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8347, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-PIK3CA antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-PI-3 kinase p110α Antibody, clone 1J4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
flow cytometry

immunohistochemistry

western blot

Cell Lines

货号
说明
物种
DLD1 Cells PIK3CA +/-, ,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
PF-04691502, ≥98% (HPLC),
物种
human

Proteins

货号
说明
物种
PI3 kinase (p110a/p85a) Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
物种
human
PI3K (p110-α/p85-α), active, His tagged from mouse and human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
mouse
PI 3-Kinase (p110α(H1047R)/p85α), 10 µg, Complex of N-terminal 6His-tagged recombinant human p110α full length, containing the mutation H1047R & untagged, recombinant, human p85α full length.,
物种
human
PI3 kinase [p110a(H1047R)/p85a] Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
物种
human
PI3 kinase [p110a(E545K)/p85a] Active human, recombinant, expressed in baculovirus infected insect cells, ≥55% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PIK3CA (2),
物种
human
MISSION® esiRNA, targeting human PIK3CA,
物种
human
MISSION® esiRNA, targeting mouse Pik3ca,
物种
mouse