PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Human PIK3CA (5290), Mouse Pik3ca (18706), Rat Pik3ca (170911), sheep PIK3CA (101110015), chicken PIK3CA (424971), dog PIK3CA (488084), domestic guinea pig Pik3ca (100735084), naked mole-rat Pik3ca (101711934), domestic cat PIK3CA (101097413), cow PIK3CA (282306)
- Human(5290) Summary: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008]
- Mouse(18706) phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
- Rat(170911) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
- sheep(101110015) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
- chicken(424971) phosphoinositide-3-kinase, catalytic, alpha polypeptide
- dog(488084) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
- domestic guinea pig(100735084) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
- naked mole-rat(101711934) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
- domestic cat(101097413) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
- cow(282306) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
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Antibodies
Monoclonal Anti-PIK3CA antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
human
ELISA
flow cytometry
immunofluorescence
western blot
flow cytometry
immunofluorescence
western blot
Anti-PIK3CA antibody produced in rabbit, ,
human, mouse
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PIK3CA antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8347, purified immunoglobulin, buffered aqueous glycerol solution,
human
immunohistochemistry
Anti-PIK3CA antibody produced in rabbit, ,
human, mouse, rat
immunohistochemistry
western blot
western blot
Anti-PI-3 kinase p110α Antibody, clone 1J4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
human, monkey
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Cell Lines
Small Molecule - Inhibitor
Proteins
PI3 kinase (p110a/p85a) Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
human
PI3K (p110-α/p85-α), active, His tagged from mouse and human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
mouse
PI 3-Kinase (p110α(H1047R)/p85α), 10 µg, Complex of N-terminal 6His-tagged recombinant human p110α full length, containing the mutation H1047R & untagged, recombinant, human p85α full length.,
human
PI3 kinase [p110a(H1047R)/p85a] Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
human
PI3 kinase [p110a(E545K)/p85a] Active human, recombinant, expressed in baculovirus infected insect cells, ≥55% (SDS-PAGE),
human