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Merck

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

别名:
5-HT(2B), 5-HT2B
物种:
UniProtKB ID:
基因ID:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

货号
说明
物种
BW 723C86, ≥98% (HPLC),
物种
human
马来酸甲基麦角新碱, United States Pharmacopeia (USP) Reference Standard,
物种
human
甲基麦角新碱 马来酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
甲基麦角新碱 马来酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
(±)-DOI 盐酸盐, ≥98% (HPLC), solid,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
马来酸甲基麦角新碱, United States Pharmacopeia (USP) Reference Standard,
物种
human
甲基麦角新碱 马来酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
甲基麦角新碱 马来酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
酮色林 (+)-酒石酸盐, ≥97%, solid,
物种
human
环苯扎林 盐酸盐, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-HTR2B 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Htr2B Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14576, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
western blot

Small Molecule - Blocker

货号
说明
物种
米赛林 盐酸盐, ,
物种
human
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human
泽麦定 二盐酸盐, solid,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
去甲替林 盐酸盐, ≥98% (HPLC), powder,
物种
human
Amoxapine, ,
物种
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
氟西汀 盐酸盐, solid,
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
米非司酮, ≥98%,
物种
human, mouse, rat
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human HTR2B,
物种
human