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Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

别名:
5-HT2A, HTR2
物种:
UniProtKB ID:
基因ID:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

货号
说明
物种
(±)-DOI 盐酸盐, ≥98% (HPLC), solid,
物种
human
(R)(−)-DOI hydrochloride, ≥98% (HPLC), solid,
物种
human
阿立哌唑 溶液, 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
α-甲基血清素 马来酸盐, ≥98% (HPLC),
物种
human
去甲替林 盐酸盐, ≥98% (HPLC), powder,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
M100907, ≥98% (HPLC),
物种
human
Haloperidol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
2,2-二苯基乙胺, 96%,
物种
rat
氟哌啶醇, United States Pharmacopeia (USP) Reference Standard,
物种
human
氟哌啶醇, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-HTR2A, affinity isolated antibody,
物种反应性
human, rat
应用
immunohistochemistry
western blot
Anti-HTR2A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
米赛林 盐酸盐, ,
物种
human
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
匹莫齐特, ,
物种
human, mouse, rat
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human
泽麦定 二盐酸盐, solid,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
苯乙胺, 99%,
物种
rat, mouse, human
苯乙胺, ≥99%,
物种
rat, mouse, human
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
苯乙胺, purified by redistillation, ≥99.5%,
物种
rat, mouse, human
盐酸曲唑酮杂质标准品, British Pharmacopoeia (BP) Reference Standard,
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
米非司酮, ≥98%,
物种
human, mouse, rat
氟哌啶醇, powder,
物种
human, rat
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Htr2a,
物种
mouse