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Merck

DDC

dopa decarboxylase (aromatic L-amino acid decarboxylase)

别名:
AADC
物种:
Human DDC (1644), Mouse Ddc (13195), Rat Ddc (24311), Zebrafish ddc (406651), fruit fly Ddc (35190), chicken DDC (420947), dog DDC (606852), domestic cat DDC (101082989), cow DDC (280762), Horse DDC (100052557) ...展开
UniProtKB ID:
P20711, C9IYA0, E7ER62, E7EU95, Q16723, Q5W5T9, Q75MJ6
基因ID:
  • Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
  • Mouse(13195) dopa decarboxylase
  • Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Zebrafish(406651) dopa decarboxylase
  • fruit fly(35190) Dopa decarboxylase
  • chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic guinea pig(100135516) dopa decarboxylase

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ELISA

货号
说明
物种
RAB1411
人多巴脱羧酶ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
HPA017742
Anti-DDC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
AMAB91089
Monoclonal Anti-DDC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2962, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
SAB2104803
Anti-DDC antibody produced in rabbit, affinity isolated antibody,
物种反应性
guinea pig, human, mouse, rat
应用
western blot
SAB1405703
Anti-DDC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
D0180
Monoclonal Anti-DOPA Decarboxylase (DDC) antibody produced in mouse, clone DDC-109, ascites fluid,
物种反应性
bovine, canine, guinea pig, human, monkey, rabbit, rat, sheep
应用
ELISA
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot

Small Molecule - Inhibitor

货号
说明
物种
B7283
多巴丝肼 盐酸盐, ≥98% (HPLC), solid,
物种
human
1095506
(S)-3-(3,4-二羟基苯基)-2-肼基-2-甲基丙酸 一水合物, United States Pharmacopeia (USP) Reference Standard,
物种
human
C1335
S-(−)-Carbidopa, ≥98% (TLC), powder,
物种
human
PHR1655
卡比多巴, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
Y0002115
峰鉴别用苄丝肼, European Pharmacopoeia (EP) Reference Standard,
物种
human

esiRNA

货号
说明
物种
EMU062541
MISSION® esiRNA, targeting mouse Ddc,
物种
mouse