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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

别名:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
物种:
UniProtKB ID:
基因ID:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase

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Antibodies

货号
说明
物种反应性
应用
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
物种反应性
human
应用
western blot
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
物种反应性
mouse
应用
western blot
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, feline, human, monkey, mouse, porcine, rat
应用
affinity binding assay
immunohistochemistry

inhibition assay

western blot
Anti-IKKa (p45) Antibody, clone 881H3, clone 881H3, from mouse,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

货号
说明
物种
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Chuk,
物种
mouse
MISSION® esiRNA, targeting human CHUK,
物种
human