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Merck

ATP6V1C1

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1

别名:
ATP6C, ATP6D, VATC, Vma5
物种:
UniProtKB ID:
基因ID:
  • Human(528) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. [provided by RefSeq, Jul 2008]
  • Mouse(66335) ATPase, H+ transporting, lysosomal V1 subunit C1
  • Rat(299971) ATPase, H+ transporting, lysosomal V1 subunit C1
  • cow(338089) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • naked mole-rat(101721955) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • sheep(101122445) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • Domestic Rabbit(100343886) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • chicken(420259) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • domestic cat(101084001) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • dog(475061) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
  • domestic guinea pig(100725980) ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1

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Antibodies

货号
说明
物种反应性
应用
Anti-ATP6V1C1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
Anti-ATP6V1C1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
Anti-ATP6V1C1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, horse, human, mouse, rabbit, rat
应用
western blot
Anti-ATP6V1C1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Atp6v1c1,
物种
mouse
MISSION® esiRNA, targeting human ATP6V1C1,
物种
human