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Merck

ADRBK1

adrenergic, beta, receptor kinase 1

别名:
BARK1, BETA-ARK1, GRK2
物种:
Human ADRBK1 (156), Mouse Adrbk1 (110355), Rat Adrbk1 (25238), naked mole-rat Adrbk1 (101708906), domestic cat ADRBK1 (101101082), cow ADRBK1 (282682), dog ADRBK1 (483701), domestic guinea pig Adrbk1 (100732560), sheep ADRBK1 (101108265), chicken ADRBK1 (426000)
UniProtKB ID:
P25098, B0ZBE1, Q13837, Q6GTT3
基因ID:
  • Human(156) Summary: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
  • Mouse(110355) adrenergic receptor kinase, beta 1
  • Rat(25238) adrenergic, beta, receptor kinase 1
  • naked mole-rat(101708906) adrenergic, beta, receptor kinase 1
  • domestic cat(101101082) adrenergic, beta, receptor kinase 1
  • cow(282682) adrenergic, beta, receptor kinase 1
  • dog(483701) adrenergic, beta, receptor kinase 1
  • domestic guinea pig(100732560) adrenergic, beta, receptor kinase 1
  • sheep(101108265) adrenergic, beta, receptor kinase 1
  • chicken(426000) adrenergic, beta, receptor kinase 1

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Antibodies

货号
说明
物种反应性
应用
G0296
AntiGRK2 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
western blot
SAB5700131
Anti-ADRBK1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
HPA048330
Anti-GRK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
SAB4504682
Anti-phospho-GRK2 (pSer685) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
SAB4500592
Anti-GRK2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot

Proteins

货号
说明
物种
SRP5034
GRK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU007911
MISSION® esiRNA, targeting mouse Adrbk1,
物种
mouse
EHU047961
MISSION® esiRNA, targeting human GRK2,
物种
human