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T5942

Sigma-Aldrich

Monoclonal Anti-14-3-3 θ/τ antibody produced in mouse

clone 3B9, purified immunoglobulin, buffered aqueous glycerol solution

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About This Item

MDL number:
MFCD03457541
UNSPSC Code:
12352203

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3B9, monoclonal

form

buffered aqueous glycerol solution

mol wt

antigen 31 kDa

species reactivity

rat, bovine, human, mouse

technique(s)

immunoprecipitation (IP): suitable
microarray: suitable
western blot: 1:5,000 using whole extracts of mouse 3T3, rat PC12, human Jurkat, or normal fibroblasts or bovine MDBK cells

isotype

IgG1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... YWHAQP4(646954)
mouse ... EG546165(546165)

Immunogen

Full-length, recombinant 14-3-3-2 θ/τ

Physical form

Solution in phosphate buffered saline, pH 7.5, containing 50% glycerol and 3 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tsutomu Nakamura et al.
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GABAergic dysfunction underlies many neurodevelopmental and psychiatric disorders. GABAergic synapses exhibit several forms of plasticity at both pre- and postsynaptic levels. NMDA receptor (NMDAR)-dependent inhibitory long-term potentiation (iLTP) at GABAergic postsynapses requires an increase in surface GABAARs through promoted exocytosis;
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We have previously shown that specific COX-2 inhibitors, including DuP 697, have anti-proliferative effects on mesothelioma cells and potentiate the cytotoxicity of pemetrexed. Here, we used a novel proteomic approach to explore the mechanism of action of this agent. COX-2-positive

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