T3080
Beta-Thromboglobulin from human platelets
≥95% (SDS-PAGE)
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About This Item
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biological source
human platelets
Quality Level
Assay
≥95% (SDS-PAGE)
form
solution
mol wt
tetramer 35,800 Da
technique(s)
cell culture | mammalian: suitable
shipped in
dry ice
storage temp.
−70°C
Application
Plasma levels of β-thromboglobulin directly correlate to the level of platelet activity and can be measured to determine platelet activity.
Biochem/physiol Actions
β-thromboglobulin was shown to inhibit megakaryocyte colony formation C.
Heparin binding protein that is used as a platelet activation marker.
Physical form
Supplied as a solution in 25 mM Hepes and 150 mM NaCl, pH 7.4
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
10 - Combustible liquids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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C W Pumphrey et al.
The American journal of cardiology, 50(6), 1258-1261 (1982-12-01)
The plasma concentration of beta-thromboglobulin (BTG), a platelet-specific protein released during platelet aggregation, is considered a sensitive marker of in vivo platelet activity. The mean plasma level in 133 asymptomatic individuals was 32.3 +/- 1.1 ng/ml, and there was no
J F Abgrall et al.
Experimental hematology, 19(3), 202-205 (1991-03-01)
The effect of highly purified human beta-thromboglobulin (beta TG), a glycoprotein present in platelet alpha granules, was tested on human bone marrow in vitro megakaryocyte (MK) colony formation. A concentration of 5 micrograms/ml of beta TG induced a 50% reduction
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