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Key Documents

T0158

Sigma-Aldrich

Calcitonin porcine

≥97% (HPLC)

Synonym(s):

Thyrocalcitonin

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About This Item

Empirical Formula (Hill Notation):
C159H232N46O45S3
CAS Number:
Molecular Weight:
3604.02
EC Number:
MDL number:
UNSPSC Code:
51111800

Assay

≥97% (HPLC)

storage temp.

−20°C

Amino Acid Sequence

Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Ser-Ala-Tyr-Trp-Arg-Asn-Leu-Asn-Asn-Phe-His-Arg-Phe-Ser-Gly-Met-Gly-Phe-Gly-Pro-Glu-Thr-Pro-NH2 [Disulfide Bridge: 1-7]

Biochem/physiol Actions

Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.

Other Notes

32 amino acid polypeptide, 8 of which are conserved across all species.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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