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SML1841

Sigma-Aldrich

Lecirelin trifluoroacetate salt

≥98% (HPLC)

Synonym(s):

Dalmarelin trifluoroacetate salt, pGlu-His-Trp-Ser-Tyr-D-tert-Leu-Leu-Arg-Pro-NHEt trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C59H84N16O12 · xC2HF3O2
CAS Number:
Molecular Weight:
1209.40 (free base basis)
UNSPSC Code:
12352200

Assay

≥98% (HPLC)

form

powder

color

white to off-white

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C59H84N16O12/c1-7-63-55(85)46-15-11-23-75(46)57(87)40(14-10-22-64-58(60)61)68-50(80)41(24-32(2)3)72-56(86)48(59(4,5)6)74-53(83)42(25-33-16-18-36(77)19-17-33)69-54(84)45(30-76)73-51(81)43(26-34-28-65-38-13-9-8-12-37(34)38)70-52(82)44(27-35-29-62-31-66-35)71-49(79)39-20-21-47(78)67-39/h8-9,12-13,16-19,28-29,31-32,39-46,48,65,76-77H,7,10-11,14-15,20-27,30H2,1-6H3,(H,62,66)(H,63,85)(H,67,78)(H,68,80)(H,69,84)(H,70,82)(H,71,79)(H,72,86)(H,73,81)(H,74,83)(H4,60,61,64)/t39-,40-,41-,42-,43-,44-,45-,46-,48-/m0/s1

InChI key

XJWIEWPGHRSZJM-MGZASHDBSA-N

Biochem/physiol Actions

Lecirelin is synthetic hypothalamic gonadotropin releasing hormone (GnRH) analogue. Lecirelin is a potent and longer lasting agonist of gonadotropin-releasing hormone receptor (GnRHR).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Dal Bosco et al.
Animal reproduction science, 150(1-2), 44-49 (2014-09-23)
This study evaluates the effect of Lecirelin (Dalmarelin(®), Fatro, Italy) diluted in different excipients (benzilic alcohol, benzoic acid and paraben) added to a seminal dose on LH concentrations, progesterone concentrations and ovarian status in rabbits. The in vitro effect on
M S Haider et al.
Animal reproduction science, 163, 24-29 (2015-11-01)
There are limited studies available on when to inseminate, if using CIDR or CIDR-GnRH protocols for optimal fertility in buffalo. Therefore, the objective of the present study was to determine the optimum time of AI in relation to CIDR removal
N Picard-Hagen et al.
Theriogenology, 84(2), 177-183 (2015-04-22)
Analogs of gonadoliberin (GnRH) are widely used in cattle to synchronize estrus and to induce ovulation, as well as for the treatment of ovarian cysts. The aim of this study was to compare the plasma profiles of LH and progesterone

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