SMB01080

Semilicoisoflavone B

≥85% (LC/MS-ELSD)

• Synonym(s): 5,7,8′-Trihydroxy-2′,2′-dimethyl-2′H-(3,6′)bi(1-benzopyranyl)-4-one
• Empirical Formula (Hill Notation): C₂₀H₁₆O₆
• CAS Number: 129280-33-7
• Molecular Weight: 352.34
• MDL number: MFCD28100710
• UNSPSC Code: 12352205
• NACRES: NA.25

Properties

• biological source: plant
• Assay: ≥85% (LC/MS-ELSD)
• form: solid
• mol wt: 352.34
• solubility: water: slightly soluble
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• InChI: 1S/C20H16O6/c1-20(2)4-3-10-5-11(6-15(23)19(10)26-20)13-9-25-16-8-12(21)7-14(22)17(16)18(13)24/h3-9,21-23H,1-2H3
• InChI key: LWZACZCRAUQSLH-UHFFFAOYSA-N

Description

General description

Semilicoisoflavone B, is an isoflavonoid belongs to the class of 7-hydroxyisoflavones, is a natural product commonly available from Glycyrrhiza Sp., Mitracarpus scaber, and Lentinus tigrinus. This plant metabolite exhibits various biological activities, including anti-inflammatory, antioxidant, anti-tumor, antiviral, and anti-allergic effects.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Semilicoisoflavone B:

• Suppresses proinflammatory cytokine production, downregulates TLR4 expression, and diminishes reactive oxygen species generation in vitro.
• Inhibits the growth and division of cancer cells by triggering apoptosis and arresting the cell cycle, offering potential for effective tumor therapy.
• Restricts Caco-2 cell proliferation, suggesting potential for metabolic syndrome therapy.

Features and Benefits

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Other Notes

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Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable