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SMB01074

Sigma-Aldrich

Sibiricose A5

≥85% (LC/MS-ELSD)

Synonym(s):

3-O-Feruloylsucrose

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About This Item

Empirical Formula (Hill Notation):
C22H30O14
CAS Number:
107912-97-0
Molecular Weight:
518.47
MDL number:
MFCD32173682
UNSPSC Code:
12352205
NACRES:
NA.25

$534.00

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biological source

plant

Assay

≥85% (LC/MS-ELSD)

form

solid

mol wt

518.47

solubility

water: slightly soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

O1[C@]([C@H]([C@@H]([C@H]1CO)O)OC(=O)\C=C\c3cc(c(cc3)O)OC)(O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)CO

InChI key

ZPEADZHVGOCGKH-YQTDNFGYSA-N

General description

Sibiricose A5, a hydroxycinnamic acid, belongs to group of compounds known as phenylpropenoyl sucroses. This bioactive natural product is commonly available from Sibiricum sp., Polygala tenuifolia and Lilium speciosum plants. It exhibits various biological activities such as anti-inflammatory, anti-depressant, neuroprotective and anti-oxidant properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Sibiricose A5 has potent antioxidant activity. It is a lactate dehydrogenase inhibitor, it displays antidepressant-like actions and it is active against Alzheimer′s disease.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Hai-Hua Tu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(11), 1278-1280 (2008-10-04)
To investigate the antidepressant components of Polygala tenuifolia. The chromatographic method was used to isolate and purify the chemical constituents, their structures were identified by spectral analysis, MTT method was applied to investigate their cytotoxic activities. Nine compounds were isolated
Xin Zhao et al.
Pharmaceutical biology, 58(1), 969-978 (2020-09-22)
Sibiricose A5 (A5), sibiricose A6 (A6), 3,6'-disinapoyl sucrose (DSS), tenuifoliside A (TFSA) and 3,4,5-trimethoxycinnamic acid (TMCA) are the main active components of Polygala tenuifolia Willd. (Polygalaceae) (PT) that are active against Alzheimer's disease. To compare the pharmacokinetics and bioavailability of

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