SAB4300609

Anti-FLT4 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-FLT41 antibody produced in rabbit, Anti-LMPH1A antibody produced in rabbit, Anti-PCL antibody produced in rabbit, Anti-VEGFR3 antibody produced in rabbit, Anti-fms-related tyrosine kinase 4 antibody produced in rabbit
• MDL number: MFCD03097363
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~160 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (L-A-S-E-E)
• NCBI accession no.: NP_002011.2
• UniProt accession no.: P35916
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... FLT4(2324)

Description

General description

Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3.

Immunogen

Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4.

Application

Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry.

Biochem/physiol Actions

Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease.

Features and Benefits

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Target description

Receptor for VEGFC. Has a tyrosine-protein kinase activity.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable