Skip to Content
Merck
All Photos(1)

Key Documents

SAB2108439

Sigma-Aldrich

Anti-TUBB6 antibody produced in rabbit

affinity isolated antibody

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

50kDa

species reactivity

rabbit, human, horse, bovine, pig, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

immunoblotting: suitable

NCBI accession no.

NM_032525

UniProt accession no.

Q9BUF5

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TUBB6(84617)

General description

Tubulin, β 6 class V (TUBB6) is encoded by a multigene family.It is located on human chromosome 18p11.21.

Immunogen

Synthetic peptide directed towards the N terminal region of human TUBB6

Biochem/physiol Actions

Tubulin, β 6 class V (TUBB6) expression expression is correlated with microtubule stability. TUBB6 expression decreases in most tumors. Mutation in TUBB6 leads to velopharyngeal dysfunction, bilateral ptosis and congenital non-progressive facial palsy.Increased production of TUBB6 causes complete disruption of microtubule network and lowers pyroptosis.

Sequence

Synthetic peptide located within the following region: QLERINVYYNESSSQKYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNFIF

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
QC31252

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death
Salinas,, et al.
Molecular Biology of the Cell, 25(1), 76-86 (2014)
A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction
Fazeli, W, et al.
Human Molecular Genetics, 26(20), 4055-4066 (2017)
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
Dempster,, et al.
Human Molecular Genetics, 20(24), 4786-4796 (2011)
Tumoral and tissue-specific expression of the major human beta-tubulin isotypes.
Leandro-Garcia LJ
Cytoskeleton (Hoboken, N.J.), 67(4), 214-223 (2010)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service