The IU measurements and conversions are designated by the WHO. In this case, the WHO has not defined an IU for rat or mouse insulin, hence a conversion factor cannot be provided for this.
RAB0817
Mouse Ins1 / Insulin-1 ELISA Kit
for serum, plasma and cell culture supernatants
Synonym(s):
Insulin
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
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species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 μIU/mL
standard curve range: 6.25-400 μIU/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Ins1(16333)
General description
The antibody pair provided in this kit recognizes Mouse Insulin 1.
Application
Mouse Ins1 / Insulin-1 ELISA Kit has been used to measure changes in serum insulin in male Sprague-Dawley rats with chemically induced diabetes.[1]
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Certain organisms such as mice, rat and xenopus possess two non-allelic insulin genes. These genes are Ins1 and Ins2, which are both functional. They encode insulin that is produced in a 1:2 ratio, respectively in the pancreas. The two genes are differentially expressed in mouse. The Ins1 gene maps to mouse chromosome 19 in the telomeric region.[2] The insulin that is synthesized in the pancreas is crucial in maintaining glucose homeostasis. Knockout of Ins-1 and Ins-2 leads to insulin deficient mice with diabetes mellitus, ketoacidosis, liver steatosis and retarded growth.[3]
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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What is the converting factor for rat and mouse insulin from IU/mL to ug/mL?
1 answer-
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Can I please get a copy of the technical info/procedure for RAB0817 (Mouse Insulin ELISA)?
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The protocol for this product is provided in the lot-specific Certificate of Analysis.
Please see the link below to review a sample Certificate:
https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/SigmaABNO/RAB0817_1212J0534.pdfHelpful?
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