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P5641

Sigma-Aldrich

Polyoxyethylene (20) oleyl ether

Synonym(s):

Brij® 98, Brij® 99, C18-1E20

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About This Item

CAS Number:
9004-98-2
MDL number:
MFCD00074369
UNSPSC Code:
12161900

description

non-ionic

InChI

1S/C20H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h9-10,21H,2-8,11-20H2,1H3/b10-9-

InChI key

KWVPFECTOKLOBL-KTKRTIGZSA-N

General description

Polyoxyethylene (20) oleyl ether is a non-ionic surfactant which can be used as structure-directing agents.

Application

Polyoxyethylene (20) oleyl ether has been used in a study to assess its effect on the transport of ibuprofen across rat skin. It has also been used in a study to investigate novel potential carriers for non-invasive drug delivery.

Legal Information

Brij is a registered trademark of Croda International PLC

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H315,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

>464.0 °F - Equilibrium method

Flash Point(C)

> 240 °C - Equilibrium method

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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E S Park et al.
International journal of pharmaceutics, 209(1-2), 109-119 (2000-11-21)
The influence of polyethoxylated non-ionic surfactants on the transport of ibuprofen across rat skin was investigated. The skin permeation of ibuprofen from a series of 17 polyoxyethylene (POE) alkyl ethers containing 5% ibuprofen was determined using Franz diffusion cells fitted
Synthesis and photocatalytic activity of co-doped mesoporous TiO"2 on Brij98/CTAB composite surfactant template
Zhou, Z., et al.
Journal of Solid State Chemistry, 183, 6-6 (2010)
Christian Wachter et al.
Journal of drug targeting, 16(7), 611-625 (2008-08-08)
Novel potential carriers for non-invasive drug delivery were prepared from polyoxyethylene(20) oleyl ether (C(18:1)EO(20)) and soybean phosphatidylcholine (SPC) in different relative molar ratios, R(e); this produced stiff SPC liposomes (2r(ves) approximately 120 nm) at one end and much smaller (2r(mic)
María Vergara-Barberán et al.
Journal of agricultural and food chemistry, 59(20), 10775-10780 (2011-09-13)
A method for the determination of fatty acids in vegetable oils by capillary electrophoresis with indirect UV-vis detection has been developed. The separation of fatty acids was optimized in terms of Brij surfactant nature and concentration and organic modifier (2-propanol)
R B Shah et al.
International journal of pharmaceutics, 341(1-2), 189-194 (2007-05-25)
In the present work, a novel application of ultrasonic measurements is detailed to characterize nano-emulsion formulations as a part of the overall Quality by Design (QbD) goal. Ultrasonic resonator technology (URT) was utilized to measure sound velocity and absorption of
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