O2501
Ornithine Transcarbamylase from Streptococcus faecalis
lyophilized powder, ≥300 units/mg protein
Synonym(s):
Carbamoylphosphate:L-Ornithine Carbamoyltransferase, OTCase, Ornithine Carbamoyl Transferase
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About This Item
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form
lyophilized powder
Quality Level
specific activity
≥300 units/mg protein
composition
Protein, ≥65% Lowry
storage temp.
−20°C
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Biochem/physiol Actions
Mutations in ornithine transcarbamylase cause Ornithine transcarbamylase deficiency which prevents the clearance of the byproduct ammonia leading to hyperammonemia.
Unit Definition
One unit will form 1.0 μmole of citrulline from ornithine and carbamyl phosphate per min at pH 8.5 at 37 °C.
Physical form
Lyophilized powder contains Tris buffer salts
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Jon Jerlström-Hultqvist et al.
Eukaryotic cell, 11(7), 864-873 (2012-05-23)
In recent years, proteomics has come of age with the development of efficient tools for purification, identification, and characterization of gene products predicted by genome projects. The intestinal protozoan Giardia intestinalis can be transfected, but there is only a limited
Taiichi Wakiya et al.
Molecular genetics and metabolism, 105(3), 404-407 (2012-01-24)
There are no objective and concrete guidelines for the management of Ornithine transcarbamylase deficiency (OTCD). Based on previous findings, we hypothesized that patients with OTCD have a low Ornithine transcarbamylase (OTC) activity in the liver, and therefore it would be
Luis Mariano Polo et al.
PloS one, 7(2), e31528-e31528 (2012-03-01)
Transcarbamylases reversibly transfer a carbamyl group from carbamylphosphate (CP) to an amine. Although aspartate transcarbamylase and ornithine transcarbamylase (OTC) are well characterized, little was known about putrescine transcarbamylase (PTC), the enzyme that generates CP for ATP production in the fermentative
Jing Wang et al.
Molecular genetics and metabolism, 106(2), 221-230 (2012-04-13)
Oligonucleotide array-based comparative genomic hybridization (aCGH) targeted to coding exons of genes of interest has been proven to be a valuable diagnostic tool to complement with Sanger sequencing for the detection of large deletions/duplications. We have developed a custom designed
Wataru Takagi et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 161(4), 331-340 (2012-01-10)
Cartilaginous fish comprise two subclasses, the Holocephali (chimaeras) and Elasmobranchii (sharks, skates and rays). Little is known about osmoregulatory mechanisms in holocephalan fishes except that they conduct urea-based osmoregulation, as in elasmobranchs. In the present study, we examined the ornithine
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