N8035

β-Nicotinamide adenine dinucleotide phosphate sodium salt

pkg of 5 mg (per vial)

• Synonym(s): β-NADP-Na, β-NADP-sodium salt, Coenzyme II sodium salt, NADP, TPN, TPN-Na, Triphosphopyridine nucleotide sodium salt
• Linear Formula: C₂₁H₂₇N₇O₁₇P₃ · Na
• CAS Number: 1184-16-3
• Molecular Weight: 765.39
• Beilstein: 4779954
• EC Number: 214-664-6
• MDL number: MFCD00036973
• UNSPSC Code: 41106305
• PubChem Substance ID: 24897850
• NACRES: NA.51

Properties

• form: powder
• packaging: pkg of 5 mg (per vial)
• mp: 175-178 °C (dec.) (lit.)
• storage temp.: −20°C
• SMILES string: [Na+].[H]O[H].NC(=O)c1ccc[n+](c1)C2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@@H]([C@@H]3O)P(O)(O)=O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
• InChI: 1S/C21H28N7O16P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(45(33,34)35)14(30)11(43-21)6-41-47(38,39)44-46(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1
• InChI key: NLIGHACCLYZCOM-FHQWUTKFSA-M

Description

Application

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Biochem/physiol Actions

Electron acceptor

Other Notes

Packaged based on NADP content as determined by UV-Vis.

This is the common form of NADP. Do not confuse with 3′-NADP or α-NADP.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves