M8877
α-Methyl-DL-m-tyrosine
Synonym(s):
α-MMT, DL-2-Methyl-3-(3-hydroxyphenyl)alanine, AMMT
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About This Item
Empirical Formula (Hill Notation):
C10H13NO3
CAS Number:
Molecular Weight:
195.22
MDL number:
UNSPSC Code:
12352200
Recommended Products
storage temp.
−20°C
SMILES string
CC(N)(Cc1cccc(O)c1)C(O)=O
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J Arita et al.
Neuroendocrinology, 38(1), 62-67 (1984-01-01)
To address the issue of whether, after morphine treatment, the reduced release of dopamine (DA) into portal blood is entirely responsible for the increased prolactin (PRL) release, the following study was conducted. The concentration of DA in plasma from a
K Ishikawa et al.
European journal of pharmacology, 120(1), 63-68 (1986-01-14)
A comparative study of the ability to block the amine pump was carried out on tricyclic antidepressants including dothiepin and northiaden in vivo. Dothiepin was found to prevent the 6-OHDA-induced depletion of cardiac noradrenaline but not the PCA-induced depletion of
Smriti Iyengar et al.
The Journal of pharmacology and experimental therapeutics, 311(2), 576-584 (2004-07-16)
5-Hydroxytryptamine (serotonin) (5-HT) and norepinephrine (NE) are implicated in modulating descending inhibitory pain pathways in the central nervous system. Duloxetine is a selective and potent dual 5-HT and NE reuptake inhibitor (SNRI). The ability of duloxetine to antagonize 5-HT depletion
J Sarkar et al.
Biochemical pharmacology, 33(4), 539-542 (1984-02-15)
In vivo administration of short acting or long acting inhibitor of monoamine oxidase elevates plasma fibrinogen level in rats. These inhibitors cannot elevate plasma fibrinogen level in rats pretreated with p-chlorophenyl alanine and alpha-methyl-meta-tyrosine, inhibitors of catecholamine and serotonin formation
M Oide
Pharmacology, 28(3), 130-138 (1984-01-01)
alpha-Methyldopa (alpha-MD) was administered intraperitoneally into adult male mice and its effect on alpha 1- and alpha 2-noradrenergic receptor binding sites in the brain was investigated, using [3H]WB-4101 and [3H]clonidine, respectively. A single injection of 50-200 mg/kg alpha-MD abolished the
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