L2261

Lanatoside C

≥97% (TLC)

• Synonym(s): Digilanide C, Digilanogen C, Isolanide, Lanatigen C
• Empirical Formula (Hill Notation): C₄₉H₇₆O₂₀
• CAS Number: 17575-22-3
• Molecular Weight: 985.12
• EC Number: 241-546-1
• MDL number: MFCD00869432
• UNSPSC Code: 12352201
• PubChem Substance ID: 24896307
• NACRES: NA.25

Properties

• Assay: ≥97% (TLC)
• form: powder
• color: white
• storage temp.: −20°C
• SMILES string: C[C@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](OC(C)=O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](C)O3)[C@@H](C)O2)O[C@H]5CC[C@@]6(C)[C@H](CC[C@@H]7[C@@H]6C[C@@H](O)[C@]8(C)[C@H](CC[C@]78O)C9=CC(=O)OC9)C5
• InChI: 1S/C49H76O20/c1-21-43(67-38-17-32(53)44(22(2)62-38)68-39-18-33(64-24(4)51)45(23(3)63-39)69-46-42(58)41(57)40(56)34(19-50)66-46)31(52)16-37(61-21)65-27-9-11-47(5)26(14-27)7-8-29-30(47)15-35(54)48(6)28(10-12-49(29,48)59)25-13-36(55)60-20-25/h13,21-23,26-35,37-46,50,52-54,56-59H,7-12,14-20H2,1-6H3/t21-,22-,23-,26-,27+,28-,29-,30+,31+,32+,33+,34-,35-,37+,38+,39+,40-,41+,42-,43-,44-,45-,46+,47+,48+,49+/m1/s1
• InChI key: JAYAGJDXJIDEKI-PTGWOZRBSA-N

Description

Application

• Cardiac glycoside sensitization in hepatocellular carcinoma: Research demonstrated that Lanatoside C enhances the sensitivity of hepatocellular carcinoma cells to TRAIL-induced apoptosis through mechanisms involving reactive oxygen species generation, p38MAPK activation, and modulation of mitochondrial transition and autophagy (Rasheduzzaman et al., 2019).


• Elimination of undifferentiated human embryonic stem cells: Lanatoside C has been shown to selectively eliminate undifferentiated human embryonic stem cells, indicating its potential use in ensuring the safety of stem cell-derived therapies (Lin et al., 2017).

Other Notes

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301,H330,H373
• Precautionary Statements: P260 - P264 - P270 - P271 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - STOT RE 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable